Quantitatively Evaluating Interactions between Patient-Derived Organoids and Autologous Immune Cells by Microfluidic Chip.

The coculture of patient-derived tumor organoids (PDOs) and autologous immune cells has been considered as a useful surrogate of tumor-immune environment. However, the immune interactions between PDOs and autologous immune cells, including immune-mediated killing behaviors and immune-related cytokine variations, have yet to be quantitatively evaluated. This study presents a microfluidic chip for quantifying interactions between PDOs and autologous immune cells (IOI-Chip).

A compact and high efficiency intracavity OPO based on periodically poled lithium niobate.

We demonstrate a compact, high efficiency and widely tunable intracavity singly resonant optical parametric oscillator (IC-OPO) based on multichannel periodically poled lithium niobate (PPLN). The IC-OPO is composed of 808 nm pump laser diode (LD), Nd:YVO laser and linear OPO. The continuous-wave (CW) mid-infrared (MIR) output laser is tunable from 2.

The complete chloroplast genome of 'black tiger 2' ( (lem.) A.C. Smith) in southeast of China and phylogenetic relationshipsAQ1.

A new super , named 'black tiger 2', was selected from variant forms of seedlings. In this study, The complete chloroplast (cp) genome of 'black tiger 2' was obtained. The complete cp genome is 145,608 in length, and contained 126 genes, including 83 protein-coding genes, 8 ribosomal RNA genes, and 35 transfer RNA genes.