Publications by authors named "Mingxue Li"

Background: Esophageal Cancer (EC) is a commonly occurring cancer of the digestive tract. The bismuth compounds from thiosemicarbazones have been observed to be active against cancer cells. However, a synthetic nine-coordinate bismuth (III) complex (complex 1) has never been assessed so far for its anticancer in the esophageal squamous cell carcinoma cell line (EC109).

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Background: Non-human primates (NPHs), such as rhesus macaques, cynomolgus monkeys, and Assamese macaques, play a crucial role in biomedical research. However, baseline cytokine and electrolyte data for these three species, particularly data stratified by age and sex, are limited. Therefore, the aim of this study was to establish and analyze age- and sex-specific cytokine and electrolyte profiles in these three species.

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The development of multifunctional films with rapidly killing microorganisms and adsorbing residual antibiotics in wastewater remains a challenging endeavor. In this work, the chitosan/zinc ion/polyoxometalate (CS/Zn/POM) multifunctional films were prepared by the freeze-drying method using chitosan, ZnO, and POM. Notably, the CS/Zn/POM films exhibited excellent bactericidal properties against Gram-positive/negative bacterial strains including (, 99.

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Nitrogen dioxide (NO) has decreased by ∼33% across over 1200 monitoring sites in China during 2015-2023, following a series of clean air policies. However, most of these sites are located in or near cities, leading to uncertainties in NO trends beyond urban regions due to limited observations. Here, we used satellite measurements to examine the differences in NO trends between urban and rural China.

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Coxsackievirus A6 (CVA6) is a primary pathogen associated with hand, foot, and mouth disease (HFMD) and is typified by fever, rashes or herpetic lesions at distinct locations. Although HFMD patients exhibit mild symptoms, a subset of patients may develop severe complications, such as viral encephalitis, myocarditis, pneumonia, and neurological disorders. However, in addition to rodent models, such as the CVA6-infected mouse model, no definitive nonhuman primate animal model or related research or analysis tool is available, which makes the development of suitable nonhuman primate animal models particularly crucial.

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The overuse of antibiotics can lead to the development of antibiotic-resistant bacteria, which can be even more difficult to treat and pose an even greater threat to public health. In order to address the issue of antibiotic-resistant bacteria, researchers currently are exploring alternative methods of sterilization that are both effective and sustainable. Polyoxometalates (POMs), as emerging transition metal oxide compounds, exhibit significant potential in various applications due to their remarkable tunable physical and chemical performance, especially in antibacterial fields.

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In this study, we selected 13 phenolic compounds containing -COOH, -CHO, -OH, and -COCH functional groups as model compounds for dissolved organic matter (DOM), and explored the redox reactions during the co-degradation of phenolic compounds with aniline disinfection by-products (DBPs) at the molecular level. When phenolic compounds and aniline DBPs were degraded, phenoxy radicals and aniline radicals were the most important intermediates. Phenoxy radicals can degrade aniline DBPs via hydrogen atom abstraction (HAA) reactions, and the reaction rates were related to the reduction potentials of the compounds.

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Carbonate (CO/HCO) have a significant impact on advanced oxidation processes (AOPs) by consuming reactive free radicals such as HO to generate CO. However, research on the mechanisms and kinetics of CO remains limited. This study investigates the degradation mechanism and kinetics of sulfonamide antibiotics (SAs) by CO through theoretical calculations.

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Article Synopsis
  • The study involves the synthesis of a trinuclear Dy-based complex using a Schiff base ligand with multiple dentate sites, leading to the creation of two different complexes with varying nuclear numbers.
  • Magnetic studies reveal that one complex shows no magnetic relaxation behavior, while the other exhibits significant single-molecule magnetic relaxation due to enhanced anisotropy and a specific energy barrier.
  • The research also explores how weak magnetic interactions impact quantum tunneling and the performance of single-molecule magnets, providing insights into designing better Dy-based complexes with desirable magnetic properties.
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  • Ketoprofen (KET) is a non-steroidal anti-inflammatory drug that poses health risks due to its accumulation in water and low biodegradability, necessitating its breakdown in aqueous environments.
  • The study investigates the degradation of KET using ozone and hydroxyl radicals (HO) through density functional theory (DFT), highlighting that while ozonation is slow, HO reactions significantly enhance degradation efficiency.
  • The research also examines factors affecting degradation efficiency, concluding that most degradation products are non-toxic, though some, particularly those with benzene rings, remain hazardous.
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  • Advanced oxidation processes using peracetic acid (PAA) are effective at removing contaminants like sulfamethoxazole (SMX) by generating reactive species that degrade these pollutants.
  • The study found that different organic radicals and acids have varying efficiencies in degrading SMX, with specific reactive radicals showing a greater ability to purify SMX.
  • The degradation of SMX primarily occurs through chemical reactions involving the benzene ring and amino groups, emphasizing the importance of these reactive radicals in AOPs using organic peracetic acids.
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  • The study explores advancements in in situ chemical oxidation (ISCO) technologies that utilize polymerization reactions to remove emerging aquatic contaminants, especially sulfonamide antibiotics (SAs).
  • Findings reveal that oligomerization, predominantly driven by the chemical structures of SAs, is the main mechanism for their removal rather than full mineralization.
  • The research also emphasizes the non-toxic nature of the resulting oligomers and proposes a new classification method (Δlog) to better understand the kinetics of SAs, ultimately improving water decontamination strategies using carbon material-based ISCO.
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Coxsackievirus B1 (CVB1), an enterovirus with multiple clinical presentations, has been associated with potential long-term consequences, including hand, foot, and mouth disease (HFMD), in some patients. However, the related animal models, transmission dynamics, and long-term tissue tropism of CVB1 have not been systematically characterized. In this study, we established a model of CVB1 respiratory infection in rhesus macaques and evaluated the clinical symptoms, viral load, and immune levels during the acute phase (0-14 days) and long-term recovery phase (15-30 days).

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Featuring low power loss and high reliability, voltage source converter medium voltage direct current (VSC-MVDC) systems have been widely employed for grid-tied renewable energy applications. To maintain high operational safety, circuit breakers are needed to isolate faulted powerlines by comprehensively considering response speed and installation cost. Research efforts have been put to realizing DC fault isolation by coordinating resistive type superconducting fault current limiter (R-SFCL) and integrated-gate-commutated-thyristor (IGCT) based hybrid DC circuit breaker.

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Coxsackievirus B3 (CVB3) is the pathogen causing hand, foot and mouth disease (HFMD), which manifests across a spectrum of clinical severity from mild to severe. However, CVB3-infected mouse models mainly demonstrate viral myocarditis and pancreatitis, failing to replicate human HFMD symptoms. Although several enteroviruses have been evaluated in Syrian hamsters and rhesus monkeys, there is no comprehensive data on CVB3.

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Objective: The aim of the study was to explore the correlation between characteristics of microbial community, pathogenic bacteria and high-risk antibiotic-resistant genes, between coastal beaches and a multi-warm-blooded host, as well as to determine potential species biomarkers for faecal source contamination on tropical coastal beaches in China.

Material And Methods: The 'One-Health' approach was used in a microbiological study of beaches and warm-blooded hosts. The microbial.

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  • Researchers developed a new photocatalytic material by combining step-scheme AgI decorated TaO heterojunctions using solvothermal and chemical deposition methods, aiming to improve visible-light absorption and photocatalytic efficiency.
  • The AgI/TaO composites showed significantly better performance in breaking down tetracycline when exposed to visible light, with the best sample exhibiting a degradation rate 7.22 times faster than TaO alone.
  • The enhanced efficiency is linked to the innovative S-scheme heterostructure and the presence of oxygen vacancies in TaO, with key radicals identified as contributing factors in the degradation process.
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  • Mineral aerosol particles influence environmental risks related to liquid crystal monomers (LCMs) by affecting their chemical reactions with ozone (O).
  • The study examined the reaction mechanisms of three LCMs with O using density functional theory, revealing that O mostly attaches to the benzene ring, producing various aromatic compounds.
  • Titanium dioxide (TiO) interacts with LCMs by adsorbing them but slightly reduces their reactivity, allowing LCMs to persist and travel further, thus increasing contamination spread.
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This paper presents a compact RF energy harvesting wireless sensor node with the antenna, rectifier, energy management circuits, and load integrated on a single printed circuit board and a total size of 53 mm × 59.77 mm × 4.5 mm.

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This paper presents a compact stacked RF energy harvester operating in the WiFi band with multi-condition adaptive energy management circuits (MCA-EMCs). The harvester is divided into antennas, impedance matching networks, rectifiers, and MCA-EMCs. The antenna is based on a polytetrafluoroethylene (PTFE) substrate using the microstrip antenna structure and a ring slot in the ground plane to reduce the antenna area by 13.

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Adjusting pH values in aqueous environments can significantly improve the efficiency by which parabens and halo-parabens are removed. In this study, 20 neutral and deprotonated species were selected as models to investigate their pH-dependent removal mechanisms and kinetics by a UV/HO process using density functional theory (DFT). Compared to neutral species, deprotonated species exhibit higher reactivity to HO due to their high electron cloud density.

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In this work, sixteen typical chlorinated and brominated aromatic disinfection by-products (DBPs) were selected as examples to investigate their different degradation mechanisms initiated by HO• and SO•. Addition reactions were the main mode of degradation of DBPs by HO•, while SO• dominated H-abstraction reactions and single electron transfer reactions. Chlorinated compounds had higher reactivity than brominated compounds.

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The reactions between chlorobenzene(CB) and ozone have been studied comprehensively in this paper. Chlorobenzene is a commonly found chlorinated aromatic volatile organic compound(VOC), and its emission into the atmosphere can cause harm to the ecosystem and human health. The frequent occurrence of mineral particles from sandstorms exerts a significant influence on the atmospheric chemistry of the troposphere.

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Renal damage in severe coronavirus disease 2019 (COVID-19) is highly associated with mortality. Finding relevant therapeutic candidates that can alleviate it is crucial. Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin-receptor blockers (ARBs) have been shown to be harmless to COVID-19 patients, but it remains elusive whether ACEIs/ARBs have protective benefits to them.

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Degradation of Chlorine-containing disinfection by-products(Cl-DBPs) on surface by electrocatalytic hydrodechlorination (EHDC) is considered a promising advanced water treatment method. Cl-DBPs have ecological toxicity and health risks so that it is urgent to degrade DBPs. We designed and verified the degradation performance of the EHDC of 18 kinds of DBPs (TAAs, TANs, TALs, TNMs, TAcAms, THMs) with different substituents led by the TiCX(X = O/OH) system by the first-principles.

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