Impact of exercise on outcomes among Chinese patients with Crohn's disease: a mixed methods study based on social media and the real world.

Objective: The effects of exercise on the health of people with Crohn's disease (CD) remain unclear. This study aimed to explore the perspective of Chinese CD patients on exercise and the quantitative relationship between exercise and patient-reported outcomes.

Methods: This study used a mixed methods design consisting of three components.

Exploratory research on the multi-life stages mesh-type model of Caenorhabditis elegans in radiation ecology.

To address the lack of effective dose quantification methods for the model organism Caenorhabditis elegans (C. elegans) in radiation ecology research, this study employs remeshing techniques to develop a comprehensive mesh-type model covering multi-life stages, from embryonic to larval (L1, L2, L3, L4) and adulthood. Using these models, Dose Coefficients (DC) for C.

Biological characteristics of molecular subtypes of ulcerative colitis characterized by ferroptosis and neutrophil infiltration.

Clinical ulcerative colitis (UC) is a heterogeneous condition. Moreover, medical interventions are nonspecific, and thus, treatment responses are inconsistent. The aim of this study was to explore the molecular subtypes and biological characteristics of UC based on ferroptosis and neutrophil gene sets.

Efficacy and safety of high-flow oxygen therapy application for chronic obstructive pulmonary disease with acute hypercapnic respiratory failure: A protocol for systematic review and meta-analysis.

Background: Presently, there are no reviews or meta-analyses comparing the efficacy and safety of high-flow oxygen therapy (HFOT) and noninvasive ventilation (NIV) as first-line treatment in exacerbated chronic obstructive pulmonary disease (COPD) patients. The present protocol is conceived to evaluate whether HFOT is noninferior to NIV in treatment of patients with COPD and acute hypercapnic respiratory failure.

Methods: We will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses reporting guidelines and the recommendations of the Cochrane Collaboration to conduct this meta-analysis.