Publications by authors named "Mingxin Ni"
This study systematically reviewed the literature on the prevention and treatment of colorectal cancer(CRC) with traditional Chinese medicine(TCM), aiming to present a more intuitive and concise overview of existing evidence. Four major Chinese databases, including CNKI, Wanfang, VIP, and SinoMed, were searched for randomized controlled trial(RCT) on TCM treatment of CRC. The retrieval period was from database inception to August 1, 2023.
View Article and Find Full Text PDFArticle Synopsis
- Shen-Bai-Jie-Du decoction (SBJDD) is a traditional Chinese herbal formula that shows promise in reducing colorectal adenoma recurrence and carcinogenesis, yet its mechanism of action is not fully understood.
- A study involving twenty-one colorectal adenoma patients and Apc mice assessed SBJDD's effects on gut microbiota, short-chain fatty acids (SCFAs), and various biological markers.
- Results indicated that SBJDD not only improved gut microbiota and SCFA production but also reduced adenoma formation, influenced inflammatory cytokines, and activated specific receptors related to gut health.
Objectives: Although colorectal cancer (CRC) is the leading cause of cancer-related morbidity and mortality, current diagnostic tests for early-stage CRC and colorectal adenoma (CRA) are suboptimal. Therefore, there is an urgent need to explore less invasive screening procedures for CRC and CRA diagnosis.
Methods: Untargeted gas chromatography-mass spectrometry (GC-MS) metabolic profiling approach was applied to identify candidate metabolites.
Background: Colorectal adenoma is benign glandular tumor of colon, the precursor of colorectal cancer. But no pharmaceutical medication is currently available to treat and prevent adenomas.
Purpose: To evaluate efficacy of Shenbai Granules, an herbal medicine formula, in reducing the recurrence of adenomas.