Global Temporal Trends in Mother-to-Child Transmission Disease Incidence Among Women of Child-Bearing Age: An Analysis of Global Burden of Disease Study 2021 Data.

Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome (HIV/AIDS), syphilis, hepatitis B and hepatitis C are the four major Mother-to-child transmission (MTCT) diseases, represent a significant public health challenge worldwide. Understanding the disease burden among women of child-bearing age (WCBA) helps to implement effective screening and treatment programs to control the MTCT diseases globally. Data on HIV/AIDS, syphilis, hepatitis B, and hepatitis C was collected from the Global Burden of Disease (GBD) 2021 database spanning 1992-2021.

[Hematological abnormalities in systemic lupus erythematosus and clinical significance thereof: comparative analysis of 236 cases].

Objective: To investigate the hematological abnormalities and their relationship to the disease activity of systemic lupus erythematosus (SLE).

Methods: The clinical data of 236 SLE patients, 29 males and 207 females with the age of confirmed diagnosis of 33.4, were divided into 3 groups: anemia group, with the hemoglobin (Hgb) < 100 g/L, including 2 subgroups, i.

[Immunotherapy of non-Hodgkin's lymphomas (NHL) by anti-CD22 antibody--review].

CD22 is a transmembrane sialoglycoprotein and a member of the immunoglobulin superfamily. Its expression is restricted to the B cell lineage and a vast majority of B cell NHLs. CD22 plays a key role in B cell development, survival, and function.