Publications by authors named "Mingxia Liang"
Although porcine liver contributes to their growth and development by nutrition production and energy supply, oxidative stress-induced hepatocyte damage is inevitable during metabolism. N-glycosylation is a common modification in oxidation; nevertheless, the effects of N-glycosylation on pig liver oxidative reactions remain undefined. In this study, liver proteins with N-glycosylation were detected in Wuzhishan (WZS) pigs between 4 and 8 months old and Large White (LW) pigs at 4 months old based on LC-MS/MS.
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- This study investigates the effects of quercetin on brain inflammation and blood-brain barrier (BBB) integrity in a mouse model affected by infection.
- Researchers found that infection caused significant brain inflammation and disrupted BBB integrity, while quercetin demonstrated anti-inflammatory and protective properties.
- The results suggest that quercetin may help maintain BBB integrity through the activation of the PI3K/Akt/Erk signaling pathway, indicating its potential as a natural treatment for infections.
Monoclonal antibodies (mAbs) that recognize and bind to specific antigens (Ags) have a wide range of applications in research, therapy, and diagnostics. However, many of these antibodies cannot bind well to the native Ags. In this study, based on the Chinese hamster ovary (CHO) cell display platform developed previously in our lab, we reported a novel artificial evolution procedure to improve the affinity of mAb against the native Ag directly using the plasma samples without purification of the native Ag.
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