Association between circadian rhythm disruption and polycystic ovary syndrome.

Objective: To explore the association of circadian rhythm disruption with polycystic ovary syndrome (PCOS) and the potential underlying mechanism in ovarian granulosa cells (GCs).

Design: Multicenter questionnaire-based survey, in vivo and ex vivo studies.

Setting: Twelve hospitals in China, animal research center, and research laboratory of a women's hospital.

The relationship between smoking and stroke: A meta-analysis.

Background: Stroke is one of the leading causes of death and disability for adult men and women worldwide, and a number of studies have explored the influences of smoking on stroke. However, few studies have discussed the relationship between stroke and smoking with consideration of the following factors: sex, the number of cigarettes smoked per day, stroke subtype, and the follow-up duration. Consequently, we aimed to extend previous work by using a systematic review to explore the relationship between stroke and cigarette smoking in reference to the above factors.

[Recurrent miscarriage and the quality of semen and sperm: a case-control study].

Objective: To analyze the relation between recurrent miscarriage and routine semen parameters.

Methods: We compared the semen parameters of normal healthy men with those of the spouses of recurrent miscarriage women through 1: 1 age-matched case-control study.

Results: Compared with the healthy controls, the men of the case group showed a significantly lower mean semen volume ([1.