Current Status of Glucagon-like Peptide-1 Receptor Agonists in Metabolic Dysfunction-associated Steatotic Liver Disease: A Clinical Perspective.

Metabolic dysfunction-associated steatotic liver disease (MASLD) is currently a pressing public health issue associated with adverse outcomes such as cirrhosis, malignancy, transplantation, and mortality. Lifestyle modifications constitute the most effective and fundamental management approach, but they often pose challenges in sustaining long-term clinical benefits. Hence, there is a critical need to enhance our understanding through pharmacological management, which unfortunately remains limited.

Bismuth oxide nanoflakes grown on defective microporous carbon endows high-efficient CO reduction at ampere level.

Carbon dioxide electroreduction is a green technology for artificial carbon sequestration, which is being delayed from industrialization due to the lack of efficient catalysts at high current conditions. Herein, the BiO nanoflakes were uniformly grown on a defective porous carbon (PC). This self-assembling BiO/PC catalyst was applied to drive CO electroreduction at 1.

Advances in the Stability of Catalysts for Electroreduction of CO to Formic Acid.

The electroreduction of CO to high-value products is a promising approach for achieving carbon neutrality. Among these products, formic acid stands out as having the most potential for industrialization due to its optimal economic value in terms of consumption and output. In recent years, the Faraday efficiency of formic acid from CO electroreduction has reached 90~100 %.

Copper-Bridge-Enhanced -Band Center Modulation of Carbon-Bismuth Heterojunction for CO Electroreduction.

Bismuth-based catalysts have advanced CO electroreduction to formic acid, but their intrinsic electronic structure remains a key obstacle to achieving a high catalytic performance. Herein, a copper bridge strategy is proposed to enhance electronic modulation effects in bismuth/carbon composites. Density functional theory calculations prove the novel hybrid orbitals on the carbon-copper-bismuth heterojunction structure (Bi-Cu/HMCS) could stabilize the HCOO* intermediate and lower the thermodynamic barrier from CO to formic acid.

Case Report: A case of gene-related early-onset Parkinson's disease and review of literature.

Background: Early onset Parkinson's disease (EOPD) is a neurodegenerative disease associated with the action ofto genetic factors. A mutated phospholipase A2 type VI gene () is considered to be one of pathogenic genes involved in EOPD development. Although EOPD caused by a mutated has been recorded in major databases, not all mutant genotypes have been reported.

Two-Scale Multimodal Medical Image Fusion Based on Structure Preservation.

Medical image fusion has an indispensable value in the medical field. Taking advantage of structure-preserving filter and deep learning, a structure preservation-based two-scale multimodal medical image fusion algorithm is proposed. First, we used a two-scale decomposition method to decompose source images into base layer components and detail layer components.