Angle-of-attack and angle-of-sideslip estimation and complementary filter design for civil aircraft.

Angle-of-Attack (AOA) and angle-of-sideslip (AOS) are critical flight parameters affecting the flight safety, and their accuracy and reliability directly impact the operating status and performance of some significant airborne systems. To enhance the redundancy and accuracy of AOA and AOS, this article investigates the problem of the airflow angles estimation and complementary filter design for civil aircraft. Specifically, an extended Kalman filter based AOA and AOS estimation method considering acceleration correction is developed to increase the redundancy.

MicroRNA-135a alleviates oxygen-glucose deprivation and reoxygenation-induced injury in neurons through regulation of GSK-3β/Nrf2 signaling.

MicroRNAs (miRNAs) have been suggested as pivotal regulators in the pathological process of cerebral ischemia and reperfusion injury. In this study, we aimed to investigate the role of miR-135a in regulating neuronal survival in cerebral ischemia and reperfusion injury using an in vitro cellular model induced by oxygen-glucose deprivation and reoxygenation (OGD/R). Our results showed that miR-135a expression was significantly decreased in neurons with OGD/R treatment.

Down-Regulation of IRF6 Protects Cortical Neurons Against Traumatic Neuronal Injury Through Activating Akt-eNOS Pathway.

Interferon regulatory factor 6 (IRF6) is a novel and unique member of the IRF family of transcription factors, and the regulation and function of IRF6 remain unknown. Recently, IRF6 was shown to be upregulated after TBI and could promote neuronal apoptosis under oxidative stress conditions. This study aimed to investigate the role of IRF6 in traumatic neuronal injury (TNI) in primary cultured mouse cortical neurons.

SEPT7 overexpression inhibits glioma cell migration by targeting the actin cytoskeleton pathway.

Glioma cell metastasis is a serious obstacle for surgical treatment and prognosis, of which locomotion of the cytoskeleton is a key contributor of cancer cell spreading. SEPT7 is documented as a cytoskeletal protein with GTPase activity and involved in glioma progression. However, the underlying mechanism of SEPT7 in glioma invasion remains unresolved.