Publications by authors named "Mingqin Zhou"
Article Synopsis
- Hepatocellular carcinoma (HCC) is a severe liver cancer with high rates of illness and death, and the study investigates the role of the protein TRPM8 in HCC progression.
- Researchers analyzed TRPM8 levels in HCC tissues and conducted various laboratory tests to understand how TRPM8 affects cell growth and movement, and used a mouse model for in vivo experiments.
- The study found that lower TRPM8 levels in HCC tissues were linked to worse patient outcomes, suggesting TRPM8 helps to slow cancer cell growth and spread through a specific signaling pathway involving RTP3 and STAT3, with a compound called AD80 promoting TRPM8 expression and potential anti-tumor effects.
Background: There is no consensus exists regarding the association between oxygen exposure (arterial oxygen tension or fraction of inspired oxygen) and outcomes for patients with mechanical ventilation. Additionally, whether the association remains persistent over time is unknown. We aimed to explore the association between exposure to different intensities of oxygen exposure over time and 28-day mortality in patients with mechanical ventilation.
View Article and Find Full Text PDFPurpose: A large proportion of patients experience chronic post-surgical pain (CPSP) following inguinal hernia repair surgery. The aim of this study was to investigate the predictive risk factors and protective factors for CPSP following inguinal hernia surgery.
Methods: After institutional ethics approval was obtained, we conducted a retrospective observational case-control study including a total of 236 adult patients undergoing elective inguinal hernia repair at a single tertiary medical center from 2014 to 2015.
Background: Fraxinus hupehensis is an endangered tree species that is endemic to in China; the species has very high commercial value because of its intricate shape and potential to improve and protect the environment. Its seeds show very low germination rates in natural conditions. Preliminary experiments indicated that gibberellin (GA) effectively stimulated the seed germination of F.
View Article and Find Full Text PDFMicroRNA156 amplifies transcription factor-associated cold stress tolerance in plant cells.
Mol Genet Genomics
April 2019
MicroRNAs may increase cold stress tolerance by regulating stress-related signal transduction pathways and by modulating the expression of transcription factors. However, the molecular mechanism by which microRNAs enhance cold stress tolerance is not fully understood. Here, we report that overexpression of rice microRNA156 (OsmiR156) results in increased cell viability and growth rate under cold stress in Arabidopsis, pine, and rice.
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