Phys Chem Chem Phys
September 2024
Point defects play a crucial role in determining the physical properties of solid-state semiconductor materials. However, theoretical investigations dedicated to point defects in higher manganese silicides (HMSs), promising thermoelectric materials composed of earth-abundant and eco-friendly elements, are surprisingly absent in the literature. Here, using first-principles calculations we systematically investigate the intrinsic and extrinsic point defects in a HMS, MnSi.
View Article and Find Full Text PDFBackground: Diabetic atherosclerosis is one of the main causes of morbidity and mortality worldwide, but its therapeutic options are limited. Liraglutide (LIR), a synthetic analog of GLP-1 approved as an anti-obesity drug by the FDA, has been reported as a promising drug for diabetic atherosclerosis. However, the main problem with LIR is its use that requires regular parenteral injections, which necessitates the improvement of drug delivery for increased efficiency and minimization of injection numbers.
View Article and Find Full Text PDFBackground: Microvascular dysfunction in patients with non-obstructive epicardial coronary may aggravate patient's symptoms or lead to various clinical events.
Objective: To investigate the correlation between dynamic single photon emission computed tomography (D-SPECT) derived coronary flow reserve (CFR) and TIMI frame count (TFC) in patients with non-obstructive epicardial coronary patients.
Methods: Patients with suspected or known stable CAD who were recommended to undergo invasive coronary angiography were prospectively enrolled in this study.
Zhonghua Xin Xue Guan Bing Za Zhi
October 2013
Objective: To explore the factors related to poor coronary collateral circulation (CCC) and the synergy effects among various factors in patients with coronary artery disease (CAD).
Methods: A total of 180 patients with coronary angiography confirmed CAD (at least one major coronary artery stenosis equal to or greater than 95%) were included in this study. Coronary collateral circulation was graded according to the Rentrop scoring system.