IL-33 aggravates extranodal NK/T cell lymphoma aggressiveness and angiogenesis by activating the Wnt/β-catenin signaling pathway.

Extranodal NK/T cell lymphoma (ENKTCL) is an extremely aggressive form of lymphoma and lacks of specific diagnostic markers. The study intended to unearth the role of interleukin-33 (IL-33) in ENKTCL. RT-qPCR was conducted to assess mRNA levels of ENKTCL tissues and cells, while western blot assay was performed for evaluating protein levels.

Orthogonal Reconstruction of Upconversion and Holographic Images for Anticounterfeiting Based on Energy Transfer.

Crosstalk-free reconstruction of multiple images within a single element can greatly boost the image capacity and information security. We herein demonstrate a viable approach by integrating upconversion and holographic images into a single holographic polymer nanocomposite. The holographic image is reconstructed through photopolymerization-induced phase separation under a 460 nm laser and identifiable under room light, while the upconversion image recognizable under a 980 nm laser is photopatterned via spatially photobleaching of the dye embedded in the upconversion nanoparticle (UCNP) shell under 365 nm light.

Highly Luminescent Liquid Crystals in Aggregation Based on Platinum(II) Complexes.

Luminescent liquid crystals (LLCs) attract considerable attention because of their broad applications in displays, chemosensors, and anti-counterfeiting. However, it remains challenging to achieve a high luminescence efficiency in LCs because of the common aggregation-caused quenching effect. Herein, we demonstrate a facile approach to designing LLCs with a high quantum yield up to 88% by deliberately tuning the aggregation behavior of platinum(II) complexes with alkoxy chains (CHO-).

One-Step and Metal-Free Synthesis of Triblock Quaterpolymers by Concurrent and Switchable Polymerization.

A one-step and metal-free route to triblock quaterpolymers from mixtures of vinyl monomers, epoxides, anhydrides, and racemic lactide (-LA) has been described, which bridges three polymerization cycles involving ring-opening copolymerization (ROCOP) of epoxides/anhydrides, ring-opening polymerization (ROP) of -LA, and RAFT polymerization of vinyl monomers. Taking advantage of the switchable polymerization between ROCOP and ROP, concurrent chain propagation of ROCOP/RAFT and ROP/RAFT sequentially occurs by using a trithiocarbonate compound with carboxylic group (TTC-COOH) as a versatile chain transfer agent. The multiple-chain transfer effect enables independent and precise control over the molecular weights of the three blocks and ensures narrow distribution of the resultant triblock quaterpolymers ( < 1.

Monochromatic "Photoinitibitor"-Mediated Holographic Photopolymer Electrolytes for Lithium-Ion Batteries.

A new polymer electrolyte based on holographic photopolymer is designed and fabricated. Ethylene carbonate (EC) and propylene carbonate (PC) are introduced as the photoinert substances. Upon laser-interference-pattern illumination, photopolymerization occurs within the constructive regions which subsequently results in a phase separation between the photogenerated polymer and unreacted EC-PC, affording holographic photopolymer electrolytes (HPEs) with a pitch of ≈740 nm.

IL-13 Contributes to Drug Resistance of NK/T-Cell Lymphoma Cells by Regulating ABCC4.

Background: Extranodal natural killer/T (NK/T) cell lymphoma, nasal type (ENKTL), represents a rare subtype of T-cell lymphomas with aggressive clinical behavior and is relatively resistant to chemotherapy. However, there is relatively poor understanding of molecular pathogenesis of multidrug resistance in ENKTL. Here, we aimed to explore the biological roles and potential mechanism of IL-13 and ABCC4 in multidrug resistance of NK/T-cell lymphoma.

Liquid Crystals under Confinement in Submicrometer Capsules.

Liquid crystal (LC) ordering and phase transition behavior under confined conditions have attracted extensive attention and enabled many applications. However, the ordering and phase transition behavior of LCs in submicrometer capsules have seldom been studied, primarily due to the lack of proper capsulizing and visualization approaches to such small LC microcapsules. Herein, we achieve submicrometer LC capsules with the sizes down to 100 nm by using emulsion-based interfacial sol-gel reaction.

Photoinitiation and Inhibition under Monochromatic Green Light for Storage of Colored 3D Images in Holographic Polymer-Dispersed Liquid Crystals.

Holographic photopolymer composites have garnered a great deal of interest in recent decades, not only because of their advantageous light sensitivity but also due to their attractive capabilities of realizing high capacity three-dimensional (3D) data storage that is long-term stable within two-dimensional (2D) thin films. For achieving high performance holographic photopolymer composites, it is of critical importance to implement precisely spatiotemporal control over the photopolymerization kinetics and gelation during holographic recording. Though a monochromatic blue light photoinitibitor has been demonstrated to be useful for improving the holographic performance, it is impractical to be employed for constructing holograms under green light due to the severe restriction of the First Law of Photochemistry, while holography under green light is highly desirable considering the relatively low cost of laser source and high tolerance to ambient vibration for image reconstruction.

Monochromatic visible light "photoinitibitor": Janus-faced initiation and inhibition for storage of colored 3D images.

Controlling the kinetics and gelation of photopolymerization is a significant challenge in the fabrication of complex three-dimensional (3D) objects as is critical in numerous imaging, lithography, and additive manufacturing techniques. We propose a novel, visible light sensitive "photoinitibitor" which simultaneously generates two distinct radicals, each with their own unique purpose-one radical each for initiation and inhibition. The Janus-faced functions of this photoinitibitor delay gelation and dramatically amplify the gelation time difference between the constructive and destructive interference regions of the exposed holographic pattern.