Promote the integrated care in China.

This article presents a brief overview of the researches on ICOPE in China, the barriers influencing the implementation of ICOPE are identified, and the recommendations are proposed to advance the ICOPE practice in China.

Implementation and impact of the World Health Organization integrated care for older people (ICOPE) program in China: a randomised controlled trial.

Background: Fragmentation of services increases health and social care burden as people live longer with higher prevalence of diseases, frailty and dependency. Local evidence for implementing person-centred integrated care is urgently needed to advance practice and policies to achieve healthy ageing.

Objective: To test the feasibility and impact of World Health Organization's (WHO) Integrated Care for Older People (ICOPE) approach in China.

Data-Driven Optimal Tracking Control for Discrete-Time Nonlinear Systems With Unknown Dynamics Using Deterministic ADP.

This article aims to solve the optimal tracking problem (OTP) for a class of discrete-time (DT) nonlinear systems with completely unknown dynamics. A novel data-driven deterministic approximate dynamic programming (ADP) algorithm is proposed to solve this kind of problem with only input-output (I/O) data. The proposed algorithm has two advantages compared to existing data-driven deterministic ADP algorithms for the OTP.

Factors associated with frailty transitions among the old-old in a community.

Aim: The study aimed to explore the factors associated with frailty transitions among the old-old (aged ≥75 years) in a community.

Methods: The participants were all from a prospective cohort study in a community in Beijing, China. Frailty states were assessed using FRAIL at baseline and at 1-year follow-up.

Development and validation of risk prediction model for identifying 30-day frailty in older inpatients with undernutrition: A multicenter cohort study.

Objective: To develop and externally validate a frailty prediction model integrating physical factors, psychological variables and routine laboratory test parameters to predict the 30-day frailty risk in older adults with undernutrition.

Methods: Based on an ongoing survey of geriatrics syndrome in elder adults across China (SGSE), this prognostic study identified the putative prognostic indicators for predicting the 30-day frailty risk of older adults with undernutrition. Using multivariable logistic regression analysis with backward elimination, the predictive model was subjected to internal (bootstrap) and external validation, and its calibration was evaluated by the calibration slope and its C statistic discriminative ability.

Parallel Image-Based Visual Servoing/Force Control of a Collaborative Delta Robot.

In this paper, a parallel Image-based visual servoing/force controller is developed in order to solve the interaction problem between the collaborative robot and the environment so that the robot can track the position trajectory and the desired force at the same time. This control methodology is based on the image-based visual servoing (IBVS) dynamic computed torque control and couples the force control feedback in parallel. Simulations are performed on a collaborative Delta robot and two types of image features are tested to determine which one is better for this parallel IBVS/force controller.

Model-Free Optimal Tracking Control of Nonlinear Input-Affine Discrete-Time Systems via an Iterative Deterministic Q-Learning Algorithm.

In this article, a novel model-free dynamic inversion-based Q-learning (DIQL) algorithm is proposed to solve the optimal tracking control (OTC) problem of unknown nonlinear input-affine discrete-time (DT) systems. Compared with the existing DIQL algorithm and the discount factor-based Q-learning (DFQL) algorithm, the proposed algorithm can eliminate the tracking error while ensuring that it is model-free and off-policy. First, a new deterministic Q-learning iterative scheme is presented, and based on this scheme, a model-based off-policy DIQL algorithm is designed.

Design of a Gough-Stewart Platform Based on Visual Servoing Controller.

Designing a robot with the best accuracy is always an attractive research direction in the robotics community. In order to create a Gough-Stewart platform with guaranteed accuracy performance for a dedicated controller, this paper describes a novel advanced optimal design methodology: control-based design methodology. This advanced optimal design method considers the controller positioning accuracy in the design process for getting the optimal geometric parameters of the robot.

Nutritional Status According to the Short-Form Mini Nutritional Assessment (MNA-SF) and Clinical Characteristics as Predictors of Length of Stay, Mortality, and Readmissions Among Older Inpatients in China: A National Study.

Background: Studies are scarce in China that explore the association of nutritional status, measured using the Short-Form Mini Nutritional Assessment (MNA-SF) and biochemical data, on adverse clinical outcomes among older inpatients. In this study, we aimed to determine the prevalence of malnutrition in tertiary hospitals of China and the associations between malnutrition and adverse clinical outcomes.

Methods: This prospective study involved 5,516 older inpatients (mean age 72.

An early predictive model of frailty for older inpatients according to nutritional risk: protocol for a cohort study in China.

Background: Previous reports suggest that the attributes of frailty are multidimensional and include nutrition, cognition, mentality, and other aspects. We aim to develop an early warning model of frailty based on nutritional risk screening and apply the frailty early warning model in the clinic to screen high-risk patients and provide corresponding intervention target information.

Methods: The proposed study includes two stages.

Associations Between Nutritional Status, Sociodemographic Characteristics, and Health-Related Variables and Health-Related Quality of Life Among Chinese Elderly Patients: A Multicenter Prospective Study.

Studies that explore the nutritional status, sociodemographic factors, mental health variables, and physical health variables that affect the health-related quality of life (HRQoL) of elderly patients are scarce in China. This study aimed to examine the association between health-related quality of life (HRQoL) and nutritional status, sociodemographic characteristics, and health-related variables among Chinese elderly patients. Participants were recruited from six tertiary-level hospitals in six provinces or municipalities/cities throughout China from October 2018 to February 2019: a total of 9,996 participants aged 65 years and older were enrolled.

Potential associated factors of functional disability in Chinese older inpatients: a multicenter cross-sectional study.

Background: There is still controversy about the relationship between aging and changes in functional ability. This study aims to describe the level of basic activities of daily living (ADL) and higher-level instrumental activities of daily living (IADL) in different age groups and explore the factors associated with functional disability in Chinese older inpatients.

Methods: This cross-sectional study surveyed 9996 older inpatients aged 65 years and older from six tertiary hospitals in China from October 2018 to February 2019.

What Is the Amount of China's Building Floor Space from 1996 to 2014?

The amount of building floor space (BFS) plays a key role in the energy and material demand prediction. Unfortunately, BFS estimation has faced the challenge of ineffective and inadequate approaches, and thus reliable data concerning China's BFS is unavailable. This study proposes a new estimation method for China's BFS and then estimates historical BFS by type in China from 1996 to 2014.

A potential urinary biomarker to determine frailty status among older adults.

Background: Association of oxidative stress biomarkers with aging and several age-related diseases is well documented. However, the possible role of these factors on frailty status in older adults has not been extensively studied.

Objective: To evaluate whether urinary 8-oxo-7,8-dihydroguanosine (8-oxo-Gsn), a biomarker of RNA oxidative damage, was independently associated with frailty.

Prevalence and associated factors for frailty among elder patients in China: a multicentre cross-sectional study.

Background: To date, most previous studies of frailty among hospitalized elderly Chinese patients have been conducted based on small samples, which cannot represent the elderly patient population. The aim of this study was to identify the prevalence of and risk factors for frailty among elderly patients in China.

Study Design And Setting: This cross-sectional study surveyed 9996 elderly patients from 6 tertiary-level hospitals in China.

Factors associated with health-related quality of life in community-dwelling elderly people in China.

Aim: Few studies have comprehensively evaluated the factors associated with health-related quality of life (HRQOL) in the elderly. The purpose of the study is to identify the factors associated with HRQOL using a comprehensive geriatric assessment of community-dwelling elderly people in Beijing, China.

Methods: A cross-sectional survey of 896 community-dwelling elderly people in Beijing was conducted through face-to-face interviews.

Prevalence and prognostic implications of sarcopenia in older patients with coronary heart disease.

Background: Sarcopenia is a progressive and generalized skeletal muscle disorder that is associated with an increased likelihood of adverse outcomes, including falls, fractures, physical disability, and mortality. However, there have been few systematic studies of the prevalence and prognostic values of sarcopenia in older patients with coronary heart disease (CHD). This study aimed to investigate the prevalence of sarcopenia in hospitalized older patients with CHD, and to prospectively evaluate the effect of sarcopenia on the short-term prognosis of these patients.

MSC-triggered metabolomic alterations in liver-resident immune cells isolated from CCl-induced mouse ALI model.

Clinical trials testing mesenchymal stem cell (MSC) as a cellular remedy for acute liver injury (ALI) are underway, but its underlying mechanism has not been thoroughly scrutinized. We highlight that the metabolomic profile of the liver-resident immune cells is significantly altered after MSC administration; its potential correlation with ALI remission is discussed in this study. C57BL/6 mice are randomly divided into three groups: the sham group, MSC-treated ALI group and PBS-treated ALI group; acute liver injury is induced by intraperitoneal injection of carbon tetrachloride.

Attitudes Toward Advance Directives Among Patients and Their Family Members in China.

Objectives: Chinese people are generally unfamiliar with the concept of advance care planning or advance directives (ACP/ADs), which raises dilemmas in life-support choice and can even affect clinical decision making. To understand and address the issues involved better, we investigated the awareness of ACP/ADs in China, as well as people's attitudes toward medical autonomy and end-of-life care.

Design: A multicenter cross-sectional survey, conducted from August 1 to December 31, 2016.

Attitudes towards Advance Care Planning and Healthcare Autonomy among Community-Dwelling Older Adults in Beijing, China.

Objectives: To investigate the preferences of ACP and healthcare autonomy in community-dwelling older Chinese adults.

Methods: A community-based cross-sectional study was conducted with older adults living in the residential estate of Chaoyang District, Beijing.

Results: 900 residents were enrolled.

Is frailty associated with short-term outcomes for elderly patients with acute coronary syndrome?

Background: Frailty is a new prognostic factor in cardiovascular medicine due to the aging and increasingly complex nature of elderly patients. It is useful and meaningful to prospectively analyze the manner in which frailty predicts short-term outcomes for elderly patients with acute coronary syndrome (ACS).

Methods: Patients aged ≥ 65 years, with diagnosis of ACS from cardiology department and geriatrics department were included from single-center.