A novel pyramid temporal causal network for weather prediction.

In the field of deep learning, sequence prediction methods have been proposed to address the weather prediction issue by using discrete weather data over a period of time to predict future weather. However, extracting and utilizing feature information of different time scales from historical meteorological data for weather prediction remains a challenge. In this paper, we propose a novel model called the Pyramid Temporal Causal Network (PTCN), which consists of a stack of multiple causal dilated blocks that can utilize multi-scale temporal features.

P-Chiral, N-phosphoryl sulfonamide Brønsted acids with an intramolecular hydrogen bond interaction that modulates organocatalysis.

Brønsted acids exemplified by OttoPhosa I (5c) were designed and evaluated in the asymmetric transfer hydrogenation of quinolines. Their catalytic properties are modulated by an intramolecular hydrogen bond that rigidifies their catalytic cavity, accelerates the reaction rate and improves enantioselectivity.

Asymmetric Library Synthesis of P-Chiral t-Butyl-Substituted Secondary and Tertiary Phosphine Oxides.

An asymmetric synthesis, amenable to library preparation of structurally diverse P-chiral t-butyl substituted secondary phosphine oxides (SPOs) and tertiary phosphine oxides (TPOs), was developed. A P-chiral H-phosphinate building block was prepared via a two-step, one-pot condensation of a chiral auxiliary with t-BuPCl, followed by hydrolysis. Nucleophilic displacement of the chiral auxiliary with Grignard reagents, followed by hydrolysis, provided a library of P-chiral SPOs.

Iridium-Catalyzed Asymmetric Transfer Hydrogenation of Alkynyl Ketones Using Sodium Formate and Ethanol as Hydrogen Sources.

A green and efficient iridium-catalyzed asymmetric transfer hydrogenation of alkynyl ketones to chiral propargylic alcohols has been developed. By using sodium formate and ethanol as hydrogen sources, a series of alkynyl ketones were hydrogenated by chiral spiro iridium catalyst ( S)-1b to provide optically active chiral propargylic alcohols with up to 98% ee under base-free conditions. This protocol provides a practical and sustainable method for the preparation of optically active propargylic alcohols.

Efficient asymmetric transfer hydrogenation of ketones in ethanol with chiral iridium complexes of spiroPAP ligands as catalysts.

Highly efficient iridium catalyzed asymmetric transfer hydrogenation of simple ketones with ethanol as a hydrogen donor has been developed. By using chiral spiro iridium catalysts (S)- a series of alkyl aryl ketones were hydrogenated to chiral alcohols with up to 98% ee.