Publications by authors named "Mingkun Shi"

Gut microbiota disruption during the weaning process is a significant factor of intestinal injury. Our previous studies have suggested that may play a critical role in causing intestinal inflammation. This study aimed to clarify the impact of on intestinal injury and the protecting effect by dihydroquercetin (DHQ) in weaned piglets.

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Background: Comprehending the patterns of alteration in boar semen quality and identifying effective nutritional interventions are crucial for enhancing the productivity of commercial pig systems. This study aimed to examine the alteration in semen quality in boars, and assess the impact of protocatechuic acid (PCA) on semen quality during the phase of declining semen quality.

Methods: In Exp.

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Obesity is becoming a major global health problem in children that can cause diseases such as type 2 diabetes and metabolic disorders, which are closely related to the gut microbiota. However, the underlying mechanism remains unclear. In this study, a significant positive correlation was observed between and obesity in children ( = 0.

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Article Synopsis
  • * The results indicate that heavier maternal weight is linked to higher litter mortality, with long-term high-fat diets (HFD) worsening these effects by altering key uterine proteins.
  • * Resveratrol showed promise by enhancing the expression of beneficial proteins and reducing litter mortality in mice, suggesting it may help counteract some obesity-related issues in pregnancy.
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The energy and metabolic state of sows will alter considerably over different phases of gestation. Maternal metabolism increases dramatically, particularly in late pregnancy. This is accompanied by the development of an increase in oxidative stress, which has a considerable negative effect on the maternal and the placenta.

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Placental function is vital to the fetal growth of sows, and resveratrol (RES) can protect cells against oxidative stress, which is one of the major factors impairing placental function. This study aimed to investigate the effect of dietary resveratrol (RES) on placental function and reproductive performance during late pregnancy in a sow model from the aspects of oxidative stress, insulin resistance, and gut microbiota. A total of 26 hybrid pregnant sows (Landrace × Yorkshire) with similar parity were randomly allocated into two groups ( = 13) and fed with a basal diet or a diet containing 200 mg/kg of resveratrol from day 85 of gestation until parturition.

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