Multidimensional Directionality-Enhanced Segmentation via large vision model.

Optical Coherence Tomography (OCT) facilitates a comprehensive examination of macular edema and associated lesions. Manual delineation of retinal fluid is labor-intensive and error-prone, necessitating an automated diagnostic and therapeutic planning mechanism. Conventional supervised learning models are hindered by dataset limitations, while Transformer-based large vision models exhibit challenges in medical image segmentation, particularly in detecting small, subtle lesions in OCT images.

Nickel-Catalyzed Selective C(sp )-F Bond Alkylation of Industrially Relevant Hydrofluoroolefin HFO-1234yf.

The selective transition-metal catalyzed C-F bond functionalization of inexpensive industrial fluorochemicals represents one of the most attractive approaches to valuable fluorinated compounds. However, the selective C(sp )-F bond carbofunctionalization of refrigerant hydrofluoroolefins (HFOs) remains challenging. Here, we report a nickel-catalyzed selective C(sp )-F bond alkylation of HFO-1234yf with alkylzinc reagents.

Nickel-catalyzed alkyl-arylation of 3,3,3-trifluoropropene.

Owing to the versatile synthetic utility of its carbon-carbon double bond, low-cost industrial chemical 3,3,3-trifluoropropene (TFP) represents one of the most straightforward and cost-efficient precursors to prepare trifluoromethylated compounds. However, only limited methods for the efficient transformations of TFP have been reported so far. Here, we report a nickel-catalyzed dicarbofunctionalization of TFP.

trans-Selective Aryldifluoroalkylation of Endocyclic Enecarbamates and Enamides by Nickel Catalysis.

Efficient methods for the dicarbofuntionalization of the cyclic alkenes 2-pyrroline and 2-azetine are limited. Particularly, the dicarbofunctionalization of endocyclic enecarbamates to achieve fluorinated compounds remains an unsolved issue. Reported here is a nickel-catalyzed trans-selective dicarbofunctionalization of N-Boc-2-pyrroline and N-Boc-2-azetine, a class of endocyclic enecarbamates previously unexplored for transition metal catalyzed dicarbofunctionalization.

Effects and mechanisms on the reduction of lead accumulation in rice grains through lime amendment.

The influence of lime amendment on the absorption and accumulation of lead (Pb) in the grains of three rice cultivars ((Dong Lian 5 (DL-5, Indica), TeYou 009 (TY-009, Hybrid Indica), and YiYou 673 (YY-673, Hybrid Indica)) was investigated and the associated mechanisms were explored. Pot experiment was conducted in heavily Pb-polluted paddy soil. The transformation of Pb species in soil and roots under different levels of lime application was studied by Pb L3-edge X-ray absorption spectroscopy (Pb L3-XAS) and BCR sequential extraction.