Palm-Sized Uric Acid Test Lab Powered by Smartphone for Proactive Gout Management.

A simple and convenient photochemical system based on a smartphone-powered photochemical dongle and disposable photochemical test strips was proposed in this paper. The components of the system were only connected with each other in a simple hot-plug way, but provided a convenient function of biological sample detection. The photochemical dongle working as a highly rigorous reflectance spectral analyzer was used to evaluate the uric acid levels of the fingertip whole blood with the participation of the photochemical test strip for the point of care, which showed good agreement (linear regression coefficient of 0.

Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation.

Cerebral cavernous malformations (CCMs) are vascular malformations that affect the central nervous system and result in cerebral hemorrhage, seizure and stroke. CCMs arise from loss-of-function mutations in one of three genes: KRIT1 (also known as CCM1), CCM2 or PDCD10 (also known as CCM3). PDCD10 mutations in humans often result in a more severe form of the disease relative to mutations in the other two CCM genes, and PDCD10-knockout mice show severe defects, the mechanistic basis for which is unclear.

The Effects of Chloride Additives on Adsorption of Heavy Metals during Incineration.

The dynamic adsorption behaviors and characteristics of heavy metals on a sorbent at different temperatures have been investigated in a previous study by the same authors. The present work focuses on the dynamic adsorption behaviors of Cr, Cu, Pb, and Cd on a sorbent (silica sand with limestone) under various chloride additive conditions (no chloride; an organic chloride, polyvinyl chloride [PVC]; and an inorganic chloride, sodium chloride [NaCl]), and estimates the adsorption saturation point of the sorbent during fluid-ized-bed incineration. The results will enable us to evaluate the effects of various chloride additives on the adsorption efficiency of heavy metals and to determine when the sor-bents should be renewed.