Publications by authors named "Mingfang Tan"

Crown roots are the main components of root systems in cereals. Elucidating the mechanisms of crown root formation is instrumental for improving nutrient absorption, stress tolerance, and yield in cereal crops. Several members of the WUSCHEL-related homeobox (WOX) and lateral organ boundaries domain (LBD) transcription factor families play essential roles in controlling crown root development in rice (Oryza sativa).

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WUS-RELATED HOMEOBOX 14 and its putative rice ortholog boost novo plant shoot regeneration

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The INDETERMINATE DOMAIN (IDD) transcription factor (TF), as a family of plant-specific zinc-finger proteins, regulates a variety of development processes and abiotic stresses in plants. IDD genes have been identified and characterized in other plants, however, the rice IDD family genes have not been investigated at genome-wide. In this study, 15 OsIDD genes were identified in rice genome and phylogenetically classified into two groups.

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Article Synopsis
  • The study aimed to investigate the expression of the nuclear antigen Ki-67 in patients with Chronic Lymphocytic Leukemia (CLL) and its relation to clinical parameters.
  • Out of 26 CLL patients analyzed, 57.7% showed positive Ki-67 expression, which correlated significantly with Rai staging, CD38 levels, and the presence of cytogenetic abnormalities related to chromosome 13q14.
  • The findings suggest that Ki-67 levels could serve as a useful indicator for assessing CLL prognosis and guiding treatment decisions.
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Objective: This study was to investigate the mRNA expression of T-bet, GATA-3, ROR γt and Foxp3 mRNA in peripheral blood of patients with chronic lymphocytic leukemia (CLL) in different stages and explore their potential role in the pathogenesis and clinical diagnosis.

Methods: A total of 46 newly diagnosed and untreated patients with CLL was chosen as patient group, including 16 patients in the stage of Binet A, 15 in the stage of Binet B, and 15 in the stage of Binet C; 20 healthy persons were selected as controls. The quantitative fluorescence PCR was adopted to detect the mRNA expression of T-bet, GATA-3, RORγt and Foxp3 in peripheral blood mononuclear cell (PBMNC).

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