Publications by authors named "Mingdong Sun"

Heavy metal pollution has become a great concern due to its adverse effects on the ecological system and human health. The present study investigated the concentrations of six common heavy metals (Cr, Cu, Zn, As, Cd, and Pb) in the Tianjin coastal area to understand their distribution, enrichment, sources, and potential ecological risk levels, focusing on the main contributors. The results showed that the concentration of Cu was high in the surface seawater (6.

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The ecological health assessment of lakes, reservoirs and wetlands can provide decision-making basis for ecosystem restoration and management. We selected 20 typical lakes, reservoirs and wetlands sampling points in Tianjin, based on physical, chemical, and biological community indicators data (zooplankton, phytoplankton, benthos, fish, large aquatic plants, riparian plants) obtained during the survey from August to September 2018. We constructed an index of ecological integrity (IEI) including physical integrity, chemical integrity, and biological integrity to evaluate their ecological health.

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Municipal wastewater treatment plants (WWTPs) are known to be important point sources of microplastic pollution in the environment because they discharge large volumes of microplastic-containing effluents into nearby rivers. However, the fate of these microplastics once they enter the urban rivers is not well understood. The present study focused on the Qing River, a typical urban river in Beijing that receives effluents from four nearby WWTPs.

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Due to unevenly distributed water resources, semi-arid regions are particularly prone to severe water shortage and quality degradation. In this study, based on long-term hydrological database (1935-2015), and the latest available water quality data sets (2011-2016), we analyzed the water crisis and its driving forces in the upper Yongding River watershed, a typical water shortage area in North China. The results showed that human induced excessive water consumption is responsible for the significantly decreased river flow over the past eight decades.

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Microplastics are an emerging pollutant of international concern due to its wide distribution through various pathways. Estuary is an important pathway for land microplastics to enter into the oceans by rivers. In this study, we hypothesized that microplastics would sink into estuary sediment during diffusion and transmission from river before entering into the sea, which results in higher accumulation of microplastics in proximity to river-estuary than in the oceans.

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China is facing great challenges to balance its natural water resource use and eco-environment protection, especially in the north semi-arid region with large water consumption due to the rapid economic growth. This highlights the urgency to use water resource carrying capacity (WRCC) as a measure to maintain the sustainable development of the human and natural water system. Here, we used a coupled model based on the system dynamics and cellular automaton models to assess the WRCC under the critical value of water resource withdrawal ratio (40%) and its sustainability in the Yongding River watershed in Beijing-Tianjin-Hebei region, where the water use highly depends on river flow and nonrenewable groundwater resources.

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With the rapid economic development in the past decades, industrialization and urbanization in China has also rapidly developed and will continue in the next decades. However, the regional water shortage has posed great challenges for the sustainable development of big cities especially in north China. Here, we used the water ecological footprint model combined with the system dynamic model to assess the water resource carrying capacity and its sustainability in Zhangjiakou City, a typical water shortage city in north China.

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Inter-basin water transfer projects might cause complex hydro-chemical and biological variation in the receiving aquatic ecosystems. Whether machine learning models can be used to predict changes in phytoplankton community composition caused by water transfer projects have rarely been studied. In the present study, we used machine learning models to predict the total algal cell densities and changes in phytoplankton community composition in Miyun reservoir caused by the middle route of the South-to-North Water Transfer Project (SNWTP).

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BACKGROUND Angiogenesis plays a significant role in complex inflammatory and angiogenic processes and is also involved in multiple myeloma (MM) pathogenesis. IL-37 is a proinflammatory cytokine in antitumor activity. Our purpose was to evaluate the IL-37 clinical significance on MM.

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The isocitrate dehydrogenase (IDH) gene mutation has been recently found, which may be involved in the occurrence of leukemia. The incidence of IDH gene mutation in the patients with adult acute myeloid leukemia (AML) is high, especially in the AML patients with normal karyotype. Different subtype and molecular biology of IDH display a different effect on the AML prognosis.

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