A model of path integration and representation of spatial context in the retrosplenial cortex.

Inspired by recent biological experiments, we simulate animals moving in different environments (open space, spiral mazes and on a treadmill) to test the performances of a simple model of the retrosplenial cortex (RSC) acting as a path integration (PI) and as a categorization mechanism. The connection between the hippocampus, RSC and the entorhinal cortex is revealed through a novel perspective. We suppose that the path integration is performed by the information coming from RSC.

Robust control of a silicone soft robot using neural networks.

This paper deals with the robust controller design problem to regulate the position of a soft robot with elastic behavior, driven by 4 cable actuators. In this work, we first used an artificial neural network to approximate the relation between these actuators and the controlled position of the soft robot, based on which two types of robust controllers (type of integral and sliding mode) are proposed. The effectiveness and the robustness of the proposed controllers have been analyzed both for the constant and the time-varying disturbances.

miR-34b attenuates trauma-induced anxiety-like behavior by targeting CRHR1.

Exposure to trauma is a potential contributor to anxiety; however, the molecular mechanisms responsible for trauma-induced anxiety require further clarification. In this study, in an aim to explore these mechanisms, we observed the changes in the hypothalamic pituitary adrenal (HPA) axis using a radioimmunoassay and the changes in anxiety-like behavior using the open field test and elevated plus maze test in a rat model following intervention with NBI‑27914, a specific corticotropin‑releasing hormone receptor 1 (CRHR1) antagonist. CRHR1 was found to be involved in trauma‑induced anxiety.