Publications by authors named "Mingchen Zhang"

Purpose: To identify the key populations for Hospital Hyperglycemia (HH) management and to assess recent trends in the management of HH.

Patients And Methods: This retrospective study analyzed 1,136,092 point-of-care blood glucose (POC-BG) measurements from 40,758 patients with HH in non-intensive care unit (non-ICU) wards at Ningbo No.2 hospital from January 2020 to December 2022.

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Nocturnal hypoglycemia is a critical problem faced by diabetic patients. Failure to intervene in time can be dangerous for patients. The existing early warning methods struggle to extract crucial information comprehensively from complex multi-source heterogeneous data.

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In recent years, artificial intelligence (AI), especially deep learning models, has increasingly been integrated into diagnosing and treating diabetic retinopathy (DR). From delving into the singular realm of ocular fundus photography to the gradual development of proteomics and other molecular approaches, from machine learning (ML) to deep learning (DL), the journey has seen a transition from a binary diagnosis of "presence or absence" to the capability of discerning the progression and severity of DR based on images from various stages of the disease course. Since the FDA approval of IDx-DR in 2018, a plethora of AI models has mushroomed, gradually gaining recognition through a myriad of clinical trials and validations.

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Article Synopsis
  • The study investigates the effects of preoperative sarcopenia and inflammatory markers on the prognosis of laryngeal cancer patients undergoing surgery.
  • A new scoring system called SFAR was developed, based on independent prognostic factors identified through statistical analysis, including preoperative sarcopenia, pTNM stage, and FAR.
  • Results show that SFAR is a significant predictor of postoperative survival, highlighting the importance of addressing systemic inflammation and sarcopenia in laryngeal cancer treatment.
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Objective: To explore causal relationship between atopic diseases (asthma and atopic dermatitis) and osteoarthritis (OA) by using mendelian randomization(MR).

Methods: Asthma and atopic dermatitis as instrumental variables were selected, searched them through IEU database, and selected the latest data with a large number of cases and single nucleotide polymorphism (SNP). Data were collected and processed using R language, inverse varianceweighted (IVW) method was adopted as main MR Evaluation method.

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Context: All types of caloric restriction are preventive against cardiovascular risk factors, but the best restriction method and most affected factors have not been identified.

Objective: The objective of this study was to explore the effects of different caloric restriction methods on various cardiovascular risk factors by horizontally comparing program advantages and disadvantages via network meta-analysis.

Data Sources: The PubMed, Web of Science, Cochrane Library, and Embase literature databases were searched (October 2013 to October 2023).

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Peripheral nerve injury is a debilitating condition that have a profound impact on the overall quality of an individual's life. The repair of peripheral nerve defects continues to present significant challenges in the field. Iron oxide magnetic nanoparticles (IONPs) have been recognized as potent nanotools for promoting the regeneration of peripheral nerves due to their capability as biological carriers and their ability to template the hydrogel structure under an external magnetic field.

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Article Synopsis
  • The study investigates the relationship between adolescents' internalizing symptoms (like anxiety and depression) and their career adaptability, determining whether these symptoms influence career development or vice versa.
  • Utilizing three-wave longitudinal data from 3,196 Chinese adolescents, the research reveals that internalizing symptoms are linked to prior career adaptability, suggesting a one-way influence rather than a reciprocal relationship.
  • The findings highlight that specific aspects of career adaptability and ambivalence can predict later anxiety symptoms and underline the need for nuanced approaches in clinical and educational settings to address these dynamic associations.
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Background: The prevalence of diabetes and obesity has been continuously rising worldwide over the last three decades, particularly in China. The prevalence varies widely among different ethnicities. In this study, we investigated the prevalence of diabetes and obesity, as well as the associated factors for diabetes in Kazakh adults in Xinjiang to improve diabetes screening.

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Objective: To analyse and discuss the association of gender differences with the risk and incidence of poststroke aphasia (PSA) and its types, and to provide evidence-based guidance for the prevention and treatment of poststroke aphasia in clinical practice.

Data Sources: Embase, PubMed, Cochrane Library and Web of Science were searched from January 1, 2002, to December 1, 2023.

Study Selection: Including the total number of strokes, aphasia, the number of different sexes or the number of PSA corresponding to different sex.

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Chinese national music is unique to China, and in the past, the single means of distribution and the audience led to the fact that knowledge of Chinese culture and history was limited to national musicians and a subset of fans. With the rapid development of the internet, the dissemination of Chinese national music is no longer limited to live performances, but is beginning to shift to media platforms. Social media has had a tremendous impact on Chinese music culture; people can search for any information they need about Chinese music.

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Background: Breathing exercises improve oxidative stress in healthy young adults and patients with diabetes, hypertension, and chronic obstructive pulmonary disease. Furthermore, the mechanism of respiratory intervention is controversial. Therefore, in this meta-analysis, we aimed to systematically evaluate the effects of breathing exercises on oxidative stress biomarkers in humans and provide evidence for the clinical application of breathing exercises.

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Background: The interparental conflict has been associated with an increased adolescents' engagement in risk-taking behaviors. However, few studies have examined the potential mediation of deviant peer affiliation and the potential moderation of school climate. Grounded in the ecological system theory, this study aimed to explore the mediating role of deviant peer affiliation and the moderating role of school climate between the association of interparental conflict and risk-taking behavior.

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Introduction: The multiple Exp-function scheme is employed for searching the multiple soliton solutions for the fractional generalized Calogero-Bogoyavlenskii-Schiff-Bogoyavlensky- Konopelchenko equation.

Objectives: Moreover, the Hirota bilinear technique is utilized to detecting the lump and interaction with two stripe soliton solutions.

Methods: The multiple Exp-function scheme and also, the semi-inverse variational principle will be used for the considered equation.

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Introduction: Although poor parental supervision has been associated with an increased adolescents' propensity for risk-taking behavior, few researchers have investigated nuanced mechanisms of how and for whom from the perspective of "family × school." Inspired by ecological system theory and self-control theory, this study aimed to investigate the mediating role of self-control and the moderating role of school climate between the link between poor parental supervision and risk-taking behavior.

Methods: Four hundred and ninety-one Chinese adolescents (231 females, M  = 15.

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Long noncoding RNA (lncRNA) plays an important role in multiple cancers. So far, the exact function of lncRNAs in papillary thyroid carcinoma (PTC) is unclear. The purposes of this work were to investigate the function and underlying mechanisms of RNF185 antisense RNA 1 (RNF185-AS1) in PTC.

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Rationale: Thyroid hormone resistance syndrome (THRS) is an inherited condition characterized by reduced responsiveness of target tissues to thyroid hormone. Due to their nonspecific symptomatic manifestations, these patients can be misdiagnosed. This study reports a pedigree with THRS caused by a mutation in the thyroid hormone receptor β (THRβ) gene.

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Background: The outbreak of the coronavirus disease-19 (COVID-19) has caused enormous stress among the public in China. Intellectual input from various aspects is needed to fight against COVID-19, including understanding of the public's emotion and behaviour and their antecedents from the psychological perspectives. Drawing upon the cognitive appraisal theory, this study examined three cognitive appraisals (i.

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Antibiotics can cause severe ecological problems for aquatic ecosystems due to their wide use and incomplete removal. Microcystis aeruginosa was exposed to different levels of erythromycin (ERY) and sulfamethoxazole (SMX) separately to assess their cytotoxic effects on harmful cyanobacteria. The production and release of the toxin MC-LR was measured, and several endpoints were investigated using flow cytometry (FCM) for 7 d.

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Objectives: Compared with unaffected individuals, patients with type 2 diabetes (T2DM) have higher risk of hypertension, and diabetes combined with hypertension can lead to server cardiovascular disease. Therefore, the purpose of this study was to establish a simple nomogram model to identify the determinants of hypertension in patients with T2DM and to quickly calculate the probability of hypertension in individuals with T2DM.

Materials And Methods: A total of 643,439 subjects participating in the national physical examination has been recruited in this cross-sectional study.

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Our study is major to establish and validate a simple type||diabetes mellitus (T2DM) screening model for identifying high-risk individuals among Chinese adults. A total of 643,439 subjects who participated in the national health examination had been enrolled in this cross-sectional study. After excluding subjects with missing data or previous medical history, 345,718 adults was included in the final analysis.

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CuCoO decoration carbon nanofibers (CNFs) as an enzyme-free glucose sensor were fabricated via electrospinning technology and carbonization treatment. The CNFs with advantages of abundant nitrogen amounts, porosity, large surface area, and superior electrical conductivity were used as an ideal matrix for CuCoO decoration. The resultant CuCoO-CNF hybrids possessed favorable properties of unique three-dimensional architecture and good crystallinity, accompanied by the CuCoO nanoparticles uniformly growing on the CNF skeleton.

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We sought to determine whether adjusting the indices used to assess beta cell function by anthropometric markers of obesity improves their clinical value in a diabetic population. We conducted a cross-sectional survey of 3732 diabetic patients who underwent a 100 g carbohydrate meal test. Insulin secretion was estimated using HOMA-B of steady state as well as △C /△G , △AUC /△AUC and CPI for dynamic state.

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Objective: In this study we aimed to propose a new computed tomography-based hemodynamic indicator to quantify the functional significance of aortic dissection and predict post intervention luminal remodeling.

Methods: Computational hemodynamics and 3D structural analyses were conducted in 51 patients with type B aortic dissection, at initial presentation and at approximately 1 month, 3 months, and 1 year post intervention. A functional index was proposed on the basis of luminal pressure difference.

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Background: Despite a rapid popular of early onset type 2 diabetes (defined as diagnosis at <40 years old) recently, there is a lack of studies on this population in economically undeveloped area. We aimed to investigate the risk factors of macrovascular complications in the early onset T2DM patients in Xinjiang, China.

Methods: A cross-sectional survey of 1736 consecutive patients with T2DM was conducted.

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