Objective: To retrospectively analyze the etiology of non-diabetic retinopathy (DR) and non-traumatic vitreous haemorrhage (VH), and the effects of different anti-vascular endothelial growth factor (VEGF) drugs.
Methods: A retrospective analysis was conducted on VH patients diagnosed as non-diabetic retinopathy or trauma. Among 101 patients treated with anti-VEGF drugs, there were 48 cases in the Conbercept group and 53 cases in the Ranibizumab group.
Aim: Vitrectomy is one of the crucial therapeutic interventions for non-traumatic and non-diabetic retinal diseases. However, the prognosis of patients undergoing this procedure and the factors affecting prognosis remain to be clarified. The aim of this study was to analyze the prognostic factors of non-traumatic and non-diabetic retinopathy complicated by vitreous hemorrhage.
View Article and Find Full Text PDFBackground: As a novel high magnification module (HMM) combining with OCT (OCT-HMM) is able to detect the microstructure of retina, we apply it to explore the ultrastructure of the macula after closure of the idiopathic macular hole (IMH) by surgery.
Methods: This is an observational case series study in which patients with full-thickness IMHs who had undergone successful macular closure by vitrectomy and internal limiting membrane peeling and healthy subjects were recruited. After comprehensive ophthalmic examinations, the images of macular area were obtained and collected by professional operators using OCT-HMM.
This study aimed to analyze the effect of the severity of obstructive sleep apnea-hypopnea syndrome (OSAHS) on diabetic nephropathy (DN) in patients with type 2 diabetes mellitus (T2DM). A total of 322 patients with T2DM participated in this cross-sectional study. OSAHS was diagnosed according to the apnea-hypopnea index (AHI) and it was categorized as follows: normal, mild, moderate, and severe.
View Article and Find Full Text PDFPurpose: To analyze the clinical features and related risk factors in diabetic retinopathy (DR) and subclinical atherosclerosis, the micro- and macro-vascular diseases in newly diagnosed type 2 diabetes mellitus (T2DM).
Methods: A retrospective study of 435 cases of inpatients with newly diagnosed T2DM from 2013-2017, and compare the 2 types of T2DM related vascular complications.
Results: The macro- and microvascular complications are not rare at this stage.
DNA Cell Biol
December 2018
(growth factor receptor-bound protein 10)-interacting protein 1 () can modulate insulin-like growth factor 1 receptor () signaling pathway, which plays an important role in regulating diabetes-associated cognitive impairment, by linking to adapter. However, it remains unclear whether endogenous expression is associated with the development of diabetes-related cognitive impairment. In this study, we measured the expression level of , , phosphorylated , phosphorylated serine/threonine protein kinase/protein kinase B ()/, and phosphorylated extracellular signal-regulated kinase ()/ in human neuroblastoma SHSY-5Y cells.
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