Enhancing the interoperability and transparency of real-world data extraction in clinical research: evaluating the feasibility and impact of a ChatGLM implementation in Chinese hospital settings.

Aims: This study aims to assess the feasibility and impact of the implementation of the ChatGLM for real-world data (RWD) extraction in hospital settings. The primary focus of this research is on the effectiveness of ChatGLM-driven data extraction compared with that of manual processes associated with the electronic source data repository (ESDR) system.

Methods And Results: The researchers developed the ESDR system, which integrates ChatGLM, electronic case report forms (eCRFs), and electronic health records.

Development of a quantitative index system for evaluating the quality of electronic medical records in disease risk intelligent prediction.

Objective: This study aimed to develop and validate a quantitative index system for evaluating the data quality of Electronic Medical Records (EMR) in disease risk prediction using Machine Learning (ML).

Materials And Methods: The index system was developed in four steps: (1) a preliminary index system was outlined based on literature review; (2) we utilized the Delphi method to structure the indicators at all levels; (3) the weights of these indicators were determined using the Analytic Hierarchy Process (AHP) method; and (4) the developed index system was empirically validated using real-world EMR data in a ML-based disease risk prediction task.

Results: The synthesis of review findings and the expert consultations led to the formulation of a three-level index system with four first-level, 11 second-level, and 33 third-level indicators.

Evolution and diversification of Mountain voles (Rodentia: Cricetidae).

The systematics of the Cricetid genus Neodon have long been fraught with uncertainty due to sampling issues and a lack of comprehensive datasets. To gain better insights into the phylogeny and evolution of Neodon, we systematically sampled Neodon across the Hengduan and Himalayan Mountains, which cover most of its range in China. Analyses of skulls, teeth, and bacular structures revealed 15 distinct patterns corresponding to 15 species of Neodon.

Phylogenomics reveals the evolution, biogeography, and diversification history of voles in the Hengduan Mountains.

The Hengduan Mountains (HDM) of China are a biodiversity hotspot whose temperate flora and fauna are among the world's richest. However, the origin and evolution of biodiversity in the HDM remain poorly understood, especially in mammals. Given that the HDM shows the highest richness of vole species in the world, we used whole-exome capture sequencing data from the currently most comprehensive sampling of HDM voles to investigate their evolutionary history and diversification patterns.

A new species of Tamiops (Rodentia, Sciuridae) from Sichuan, China.

During a small mammal survey in Wanglang National Natural Reserve, Sichuan, China in AugustOctober 2018, we collected four specimens of an Asiatic striped squirrel (genus Tamiops) that could not be assigned morphologically to any described species. Phylogenetic analyses of CYTB and nuDNA sequences strongly supported them in the genus Tamiops. The p-distances of CYTB between these individuals and other species of Tamiops ranged from 17.

Multilocus phylogeny and cryptic diversity of white-toothed shrews (Mammalia, Eulipotyphla, Crocidura) in China.

Background: Crocidura, the most speciose mammalian genus, occurs across much of Asia, Europe and Africa. The taxonomy of Chinese representatives has been studied primarily based on cursory morphological comparisons and their molecular phylogenetic analyses remain unexplored. In order to understand the phylogeny of this group in China, we estimated the first multilocus phylogeny and conducted species delimitation, including taxon sampling throughout their distribution range.

Out of Tibet: Genomic Perspectives on the Evolutionary History of Extant Pikas.

Pikas are widely distributed in the Northern Hemisphere and are highly adapted to cold and alpine environments. They are one of the most complex and problematic groups in mammalian systematics, and the origin and evolutionary history of extant pikas remain controversial. In this study, we sequenced the whole coding sequences of 105 pika samples (29 named species and 1 putative new species) and obtained DNA data for more than 10,000 genes.

How many species of and occur in China? A survey based on mitochondrial cyt b and morphological analyses.

(mice) and (rats) are the top rodent reservoirs for zoonoses in China, yet little is known about their diversity. We reexamined the alpha diversity of these two genera based on a new collection of specimens from China and their cyt sequences in GenBank. We also tested whether species could be identified using external and craniodental measurements exclusively.

Taxonomic position of Chinese voles of the tribe Arvicolini and the description of 2 new species from Xizang, China.

China has 26 species in the tribe Arvicolini. The taxonomic status of these voles remains controversial despite much effort. Herein, we evaluate the taxonomic position of 22 species plus 2 unidentified taxa using mitochondrial DNA gene sequences ().