[Experimental research of targeting hTERT gene inhibited in hepatocellular carcinoma therapy by RNA interference].

Background & Objective: RNA interference (RNAi) is a new gene blocking technology that silences target gene at post-transcription level induced by the small interference RNA (siRNA). RNAi has been demonstrated great prospect in gene functional research and gene therapy areas. Nowadays, RNAi has been reported to be used to inhibit the expression of endogenous genes including cyclophilin, GAPDH, p53, and c-myc; and there were some progresses in the therapy of the diseases caused by AIDS and hepatitis viruses with RNAi.

[Detection of platelet Ca2+(i), CD62P, CD63 and plasma CD62P in cirrhosis patients].

Objectives: To study on the relationship between platelet Ca2+(i), CD62P, CD63, serum CD62P (SCD62P) and cirrhosis patients.

Methods: Platelet CD62P, CD63 were determined with flow cytometry, SCD63P with ELISA, and Ca2+(i) in platelet was determined with fluorophotometry.

Results: Platelet Ca2+(i), CD62P, CD63, and SCD62P levels in cirrhosis patients were (103.