Publications by authors named "Ming-kui Du"
Objective: To report a group of special patients showing a normal signal intensity of MRI with a positive discography and discuss its pathogenesis and clinical significance.
Methods: From August 2003 to November 2008, 288 patients with chronic low back pain were treated. Of these patients, 12 showed a normal intensity signal of MRI in lumbar intervertebral discs with a positive discography.
Article Synopsis
- The study aimed to understand the natural progression and treatment outcomes for patients with discogenic low back pain, to enhance clinical guidance for managing the condition.
- A total of 72 patients were hospitalized and divided into two groups: one received an intradiscal injection of methylene blue and the other a placebo, with follow-up assessments conducted over four years.
- Results showed that most patients experienced little to no improvement in their symptoms over time, indicating that discogenic low back pain tends to be a chronic and unchanging condition.