[Preservation with high-pressure carbon monoxide better protects ex vivo rabbit heart function than conventional cardioplegic solution preservation].

Objective: To investigate the protective effect of high-pressure carbon monoxide for preservation of ex vivo rabbit heart graft in comparison with the conventional HTK cardioplegic solution preservation.

Methods: Heart grafts isolated from 85 New Zealand rabbits were randomly divided into Naive group (n=5), HTK group (n=40) and CO group (n=40). The grafts underwent no preservation procedures in Naive group, preserved at 4 degrees celsius; in HTK cardioplegic solution in HTK group, and preserved at 4 degrees celsius; in a high-pressure tank (PO2: PCO=3200 hPa: 800 hPa) in CO group with Krebs-Henseleit solution perfusion but without cardioplegic solution.

[Early surgical outcomes of coronary heart disease with severe ischemic mitral regurgitation].

Objective: To summarize the experience with surgical treatment of coronary artery disease with severe ischemic mitral valve regurgitation (IMR).

Methods: From January 2006 to December 2009, 45 patients (35 males, 10 females aged 32-74 years) with the diagnosis of coronary artery disease complicated by IMR underwent coronary artery bypass grafting (CABG) combined with mitral valve plasty (MVP, 24 cases) or mitral valve replacement (MVR, 21 cases).

Results: Perioperative deaths occurred in 2 cases due to multiple organ failure (MOF).

[Early and mid-term results after 17 mm St Jude Regent mechanical valve replacement in 44 patients with small aortic root].

Objective: To analyze the changes in the cardiac function after St. Jude Regent mechanical valve replacement and assess the prosthesis-patient matching.

Methods: From October 2007 to March 2009, 44 patients received implantation of 17 mm St.

[Surgical treatment of 128 cases of constrictive pericarditis].

Objective: To summarize the experience with surgical treatment of constrictive pericarditis.

Methods: A retrospective analysis of the post-operative clinical data was conducted in 128 surgical patients with chronic constrictive pericarditis.

Results: Two early postoperative death occurred in this group due to severe low cardiac output syndrome, with the mortality rate of 1.

[Transepicardial autologous transplantation of bone marrow mononuclear cells for acute myocardial infarction].

Objective: To test the effect of intramyocardial injection of autologous bone marrow mononuclear cells (MNCs) in improving the cardiac function and myocardial revascularization in miniswine models of myocardial infarction.

Methods: The miniswine models of myocardial infarction established by ligation of the anterior descending coronary artery were divided into 3 groups including a control and two MNC injection groups. Autologous bone marrow MNCs were injected via the epicardium into the infarcted area in the latter two groups at 1 and 2 weeks after the infarction, respectively.