Publications by authors named "Ming-huan Zheng"

Article Synopsis
  • * Researchers used two-dimensional electrophoresis and spectrometry to identify proteins in each strain, finding 502 proteins in 053426 and 380 proteins in 053442, linked to various cellular functions.
  • * The clinical strain 053442 showed higher levels of virulence factors and proteins associated with infection, while the carrier strain 053426 had lower levels, suggesting these differences may explain their varied pathogenicity and roles in the outbreaks.
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Objective: To investigate the differences between the sequences of papA and papG of UPEC4030 strain and the related genes, to better understand the genetic variation of UPEC4030 papA and its combination forms with papG so as to identify if it was a new genotype.

Methods: Cloning and sequencing methods were used to analyze the sequences of papG and papA of UPEC4030 strain and to compare their related sequences.

Results: Through sequence analysis of papA, it was revealed that there was a 722 bp gene, encoding 192 amino acid polypeptide.

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In this study, 68 group A streptococcus (GAS) isolates associated with two outbreaks of acute glomerulonephritis (AGN) in China were analyzed by emm typing. A total of 11 different emm types were identified. Analysis of emm type distribution suggested that AGN outbreaks in two counties were caused by emm60.

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