Publications by authors named "Ming-Yi Koh"
Introduction: Lipoprotein(a) [Lp(a)] is an established independent causal risk factor for cardiovascular disease and atherosclerosis. However, its association with young-onset ischemic stroke is not well-established. A systematic review and meta-analysis was performed to investigate the association of elevated Lp(a) with young ischemic stroke.
View Article and Find Full Text PDFBackground: Cognitive impairment, and in the long term Alzheimer's disease, vascular, or mixed dementia, are potential complications of moyamoya disease (MMD), of which the prevalence and associations are not well established.
Objective: We performed a systematic review and meta-analysis to investigate the prevalence of cognitive impairment in adult patients with MMD as well as its clinical and demographic correlates.
Methods: We performed a systematic search of four electronic databases: PubMed (MEDLINE), EMBASE, Scopus, and Cochrane Library, profiling studies from inception until 7 May 2023.
Article Synopsis
- The study investigates the effectiveness and safety of using stent retrievers (SR) versus aspiration catheters (AC) in treating acute ischaemic stroke caused by distal medium vessel occlusion (AIS-DMVO).
- A systematic review of 13 studies involving 1881 patients found that the combination of SR and primary combined techniques resulted in higher rates of functional independence and lower mortality compared to AC alone.
- While both methods had similar outcomes for successful recanalisation and safety concerns, SR alone showed a significantly higher odds of successful recanalisation compared to AC, indicating possible advantages for SR/PC techniques.
Photorealistic 3D models (PR3DM) have great potential to supplement anatomy education; however, there is evidence that realism can increase cognitive load and negatively impact anatomy learning, particularly in students with decreased spatial ability. These differing viewpoints have resulted in difficulty in incorporating PR3DM when designing anatomy courses. To determine the effects of spatial ability on anatomy learning and reported intrinsic cognitive load using a drawing assessment, and of PR3DM versus an Artistic colour-coded 3D model (A3DM) on extraneous cognitive load and learning performance.
View Article and Find Full Text PDFIntroduction: A patent foramen ovale (PFO) may coexist with other potential embolic sources (PESs) in patients with embolic stroke of undetermined source (ESUS), leading to difficulty in attributing the stroke to either the PFO or other PESs. We aimed to investigate the prevalence and predictors of concomitant PESs in ESUS patients with PFOs.
Methods: A retrospective cohort study was conducted in a tertiary stroke centre.
Background And Aims: Patients with Moyamoya disease (MMD) can present with ischaemic or haemorrhagic stroke. There is no good evidence for treatment strategies in MMD-associated acute ischaemic stroke (AIS), particularly for treatments like intravenous thrombolysis (IVT) and endovascular thrombectomy (ET). As the intracranial vessels are friable in MMD, and the risk of bleeding is high, the use of IVT and ET is controversial.
View Article and Find Full Text PDF