Classification and hemodynamic characteristics of delayed intracerebral hemorrhage following stent-assisted coil embolism in unruptured intracranial aneurysms.

Background And Objective: Stent-assisted coil (SAC) embolization is a commonly used endovascular treatment for unruptured intracranial aneurysms (UIAs) but can be associated with symptomatic delayed intracerebral hemorrhage (DICH). Our study aimed to investigate the hemodynamic risk factors contributing to DICH following SAC embolization and to establish a classification for DICH predicated on hemodynamic profiles.

Methods: This retrospective study included patients with UIAs located in the internal carotid artery (ICA) treated with SAC embolization at our institution from January 2021 to January 2022.

Virtual simulation with AneuShape™ software for microcatheter shaping in intracranial aneurysm coiling: a validation study.

Background: The shaping of an accurate and stable microcatheter plays a vital role in the successful embolization of intracranial aneurysms. Our study aimed to investigate the application and the role of AneuShape™ software in microcatheter shaping for intracranial aneurysm embolization.

Methods: From January 2021 to June 2022, 105 patients with single unruptured intracranial aneurysms were retrospectively analyzed with or without AneuShape™ software to assist in microcatheter shaping.

A 58-Year Old Male with Cognitive Deteriorations Caused by Septum Pellucidum Cyst: A Case Report.

Dementia is known to be induced by vascular dementia and certain neurodegenerative diseases. The presenting features of disordered memory, intellect and personality often result in referral to a neurologist initially. Septum pellucidum cyst (SPC) is a rare clinical finding and defined as a cystic structure between the lateral ventricles.

B10 Cells Ameliorate the Progression of Lupus Nephritis by Attenuating Glomerular Endothelial Cell Injury.

Background/aim: B10 cells are generally considered to inhibit the kidney injury in systemic lupus erythematosus (SLE) mouse models, but recently this function of B10 cells was denied by the lineage-specific deletion of IL-10 from B cells. Thus, this study aimed to determine whether and how B10 cells play a protective role in lupus nephritis (LN).

Methods: LN and non-LN SLE patients without receiving any treatments were recruited, and the percentages of circulating B10 cell were determined.

EphB2 contributes to human naive B-cell activation and is regulated by miR-185.

EphB2 is an important member of the receptor tyrosine kinases. Recently, EphB2 was shown to facilitate T-cell migration and monocyte activation. However, the effects of EphB2 on B cells remain unknown.

Cardiac fibroblasts recruit Th17 cells infiltration into myocardium by secreting CCL20 in CVB3-induced acute viral myocarditis.

Aims: Th17 cells contributed to myocardial inflammatory injury in acute viral myocarditis (AVMC), and the migration of these cells were mainly mediated by CCL20-secreting inflammatory cells. However, whether and how the resident cells such as cardiomyocytes and cardiac fibroblasts could mediate Th17 cell migration into the heart remains unclear in AVMC.

Methods: The effect of CCL20 on the dynamic alterations of intracardiac Th17 cells and disease severity were investigated through the neutralization of CCL20 in AVMC mice.

Organo- and hydrogelators based on luminescent monocationic terpyridyl platinum(II) complexes with biphenylacetylide ligands.

A series of phosphorescent terpyridyl platinum(II) complexes with ancillary biphenylacetylide ligands, namely, [(R(3)tpy)PtC≡C(biphenyl)]X (R=tBu, H, or Et(2)N; tpy=2,2';6',2''-terpyridyl; X is an anion) were synthesized and structurally characterized by various spectroscopic techniques and X-ray diffraction methods. Despite a lack of long alkyl chain(s) or hydrogen-bonding motif(s), complexes [(tpy)PtC≡C(biphenyl)]Cl and [(tBu(3)tpy)PtC≡C(biphenyl)]X (X=Cl, ClO(4), PF(6), or BF(4)) were found to gelate water and organic solvents, respectively. The self-aggregation of these complexes in solutions and the resulting gels were investigated with variable-temperature (VT) (1)H NMR spectroscopy, polarized optical microscopy, and absorption/emission spectroscopy.

Organic triplet excited states of gold(I) complexes with oligo(o- or m-phenyleneethynylene) ligands: conjunction of steady-state and time-resolved spectroscopic studies on exciton delocalization and emission pathways.

A series of mononuclear and binuclear gold(I) complexes containing oligo(o- or m-phenyleneethynylene) (PE) ligands, namely [PhC≡C(C(6)H(4)-1,2-C≡C)(n-1)Au(PCy(3))] (n = 2-4, 4a-c), [μ-{C≡C-(1,2-C(6)H(4)C≡C)(n)}{Au(PCy(3))}(2)] (n = 1-6, 8, 5a-g), [PhC≡C(C(6)H(4)-1,3-C≡C)(n-1)Au(PCy(3))] (n = 2-4, 6a-c), and [μ-{C≡C-(1,3-C(6)H(4)C≡C)(n)}{Au(PCy(3))}(2)] (n = 1, 2, 7a,b), were synthesized and structurally characterized. Extensive spectroscopic measurements have been performed by applying combined methods of femtosecond transient absorption (fs-TA), fs time-resolved fluorescence (fs-TRF), and nanosecond time-resolved emission (ns-TRE) coupled with steady-state absorption and emission spectroscopy at both ambient and low (77 K) temperatures to directly probe the temporal evolution of the excited states and to determine the dynamics and spectral signatures for the involved singlet (S(1)) and triplet (T(1)) excited states. The results reveal that S(1) and T(1) both feature ligand-centered electronic transitions with ππ* character associated with the phenyl and acetylene moieties.

Structures and solvatochromic phosphorescence of dicationic terpyridyl-platinum(II) complexes with foldable oligo(ortho-phenyleneethynylene) bridging ligands.

A series of binuclear organoplatinum(II) complexes, [(tBu3tpy)Pt--(C[triple chemical bond]C--1,2-C6H4)n--C[triple chemical bond]C--Pt(tBu3tpy)][ClO4]2 (1-7, n=1, 2, 3, 4, 5, 6, 8; tBu3tpy=4,4',4''-tri-tert-butyl-2,2':6',2''-terpyridine) with foldable oligo(ortho-phenyleneethynylene) linkers were prepared and characterized by spectroscopic methods and/or X-ray crystallographic analyses. In the crystal structures of 32.5 CH3OH, 5CH3CN, and 64 CH3CN, each of the bridging ortho-phenyleneethynylene ligands has a partially folded conformation.