Palladium-catalyzed amidation of carbazole derivatives hydroamination of isocyanates.

The first amidation of carbazoles at the N9 position palladium-catalyzed hydroamination of isocyanates is demonstrated. This simple, general and efficient method could deliver a wide range of carbazole--carboxamides in up to 99% yield. The salient features of this transformation include simple conditions with no need for a strong base, high chemo- and regio-selectivities and good functional group tolerance.