Publications by authors named "Ming-Shui Wu"
Visceral leishmaniasis (VL) caused by Leishmania spp. is an important vector-borne and largely zoonotic disease. In China, three epidemiological types of VL have been described: anthroponotic VL (AVL), mountain-type zoonotic VL (MT-ZVL), and desert-type ZVL (DT-ZVL).
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- Mouse models are not as accurate as rat models for studying toxoplasmosis in humans due to differences in clinical symptoms.
- The study identified significant variations in brain cyst counts among different strains of adult and newborn rats after being infected with Toxoplasma gondii, particularly noting that Fischer 344 rats had the highest cyst counts.
- The research suggests that the differences in infection rates may be connected to genetic factors influencing the rats' immune responses, emphasizing the importance of both genetic background and age in the severity of T.gondii infection.