C(sp(3))-C(sp(3)) bond cleavage in the palladium-catalyzed aminohydroxylation of allylic hydrazones using atmospheric oxygen as the sole oxidant.

A C-C bond cleavage was observed in the palladium-catalyzed aminohydroxylation of allylic hydrazones, using atmospheric oxygen as the sole oxidant. This reaction could also proceed in a one-pot manner, starting from keto-alkene compounds and phenylhydrazine.

Radical-mediated diamination of alkenes with phenylhydrazine and azodicarboxylates: highly diastereoselective synthesis of trans-diamines from cycloalkenes.

Metal-free synthesis: Diamination of alkenes by using phenylhydrazine and azodicarboxylates could be achieved in a one-pot manner under very mild conditions (see scheme; Boc = tert-butoxycarbonyl). This process works with the assistance of acetic acid by means of a radical mechanism and displays a high trans selectivity when cycloalkene substrates were used in the reaction.

Palladium-catalyzed C-C bond formation of arylhydrazines with olefins via carbon-nitrogen bond cleavage.

The unactivated carbon-nitrogen bond of various aryl hydrazines was cleaved under very mild conditions by Pd(0) with the assistance of Pd(II). The in situ generated aryl palladium complex readily takes part in the C-C bond formation with olefins. This study offered a new mode of C-Pd bond formation, which will spur the development of palladium-catalyzed cross-coupling in the future.

Palladium-catalyzed oxime assisted intramolecular dioxygenation of alkenes with 1 atm of air as the sole oxidant.

This paper describes a palladium-catalyzed oxime assisted intramolecular dioxygenation of alkenes by using 1 atm of air as the sole oxidant under extremely mild conditions, which demonstrated the feasibility of incorporating atmospheric oxygen into synthetically useful products under 1 atm of air at room temperature.