Publications by authors named "Ming-Kai Yang"
J Invest Dermatol
November 2020
Article Synopsis
- Hair follicles go through cycles of growth, rest, and regression supported by stem cells, and certain mutations can disrupt these processes, leading to hair loss and skin inflammation.
- An overexpression of the Gsdma3 gene in mice causes significant disruptions in hair cycling, including cell death during key stages that leads to hair follicle degeneration.
- The study reveals that while immune cells are present in the affected areas, they do not seem to directly cause hair follicle damage, suggesting that Gsdma3 plays a critical role in maintaining the hair follicle stem cell environment.
