Insight into Dysmenorrhea Research from 1992 to 2022: A Bibliometric Analysis.

Dysmenorrhea, classified as primary dysmenorrhea and secondary dysmenorrhea, is a common gynecological symptom that seriously affects female daily life. At present, studies on dysmenorrhea are numerous and complex. To better reflect the trend and innovative progress of dysmenorrhea-related research, this study screened papers on the Web of Science from January 1, 1992, to December 31, 2022.

Supplementation of Polysaccharide Combined with Aerobic Exercise Ameliorates High-Fat-Induced Nonalcoholic Steatohepatitis via AMPK/PPARα/PGC-1α Pathway.

Nonalcoholic steatohepatitis (NASH) is a subtype of nonalcoholic fatty liver disease (NAFLD). Either polysaccharide (LBP) or aerobic exercise (AE) has been reported to be beneficial to hepatic lipid metabolism. However, whether the combination of LBP with AE improves lipid accumulation of NASH remains unknown.

Self-Assembling Peptide Scaffold Carrying Neural-Cell Adhesion Molecule-Derived Mimetic-Peptide Transplantation Promotes Proliferation and Stimulates Neurite Extension by Modulating Tau Phosphorylation and Calpain/Glycogen Synthase Kinase 3 beta (GSK-3β) in Neurons.

BACKGROUND Self-assembling peptide scaffolds have been extensively applied in tissue engineering. Many investigations have modified self-assembling peptide scaffolds by integrating functional motifs, with promising applications. This study aimed to generate a novel RADA16 self-assembling peptide scaffold integrating a neural-cell adhesion molecule-derived mimetic-peptide (SIDRVEPYSSTAQ) and evaluated the effects on neuron proliferation.

[Acupuncture combined with cinesiotherapy cupping for knee osteoarthritis with stagnation and blood stasis syndrome: a randomized controlled trial].

Objective: To compare the clinical efficacy between acupuncture combined with cinesiotherapy cupping and acupuncture combined with conventional cupping for knee osteoarthritis (KOA) with stagnation and blood stasis syndrome, and to seek a better solution for KOA.

Methods: A total of 78 patients of KOA with stagnation and blood stasis syndrome were randomly divided into an observation group and a control group, 39 cases in each group (3 cases in the observation group and 2 cases in the control group lost contact). Both groups were treated with acupuncture at Neixiyan (EX-LE 4), Dubi (ST 35), Xuehai (SP 10), Liangqiu (ST 34), Heding (EX-LE 2), Zusanli (ST 36), Yinlingquan (SP 9), Yanglingquan (GB 34) and Xuanzhong (GB 39).

Therapeutic Advantages of Internal Fixation with Kirschner Wire and Bone Grafting via Limited Tarsal Sinus Incision Approach for Displaced Intra-Articular Calcaneal Fractures of Children.

BACKGROUND Displaced intra-articular calcaneal fractures (DIACF) are a serious injury and are clinically considered to be an important source of disability. This study investigated therapeutic effects of internal fixation with Kirschner wire and bone grafting via limited tarsal sinus incision in pediatric DIACF. MATERIAL AND METHODS This retrospective study included pediatric DIACF patients admitted to our department from June 2010 to February 2014.

Development of efficient docking strategies and structure-activity relationship study of the c-Met type II inhibitors.

c-Met is a transmembrane receptor tyrosine kinase and an important therapeutic target for anticancer drugs. In the present study, we systematically investigated the influence of a range of parameters on the correlation between experimental and calculated binding free energies of type II c-Met inhibitors. We especially focused on evaluating the impact of different force fields, binding energy calculation methods, docking protocols, conformation sampling strategies, and conformations of the binding site captured in several crystallographic structures.

Long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 regulates the expression of Gli2 by miR-202 to strengthen gastric cancer progression.

Background: Gastric cancer (GC) is one of the most common malignancies and ranks the second leading cause of cancer death worldwide. Some studies had reported the tumor-promoting effects of long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) as a competing endogenous RNA (ceRNA) by sponging to microRNAs. However, the molecular mechanism of ceRNA regulatory pathway involving MALAT1 in GC remains unclear.

rhHMGB1 drives osteoblast migration in a TLR2/TLR4- and NF-κB-dependent manner.

Osteoblast migration is significant in skeletal development. Recently, high mobility group box 1 protein (HMGB1) has been shown to highly expressed in cartilage to regulate endochondral ossification. Nevertheless, whether HMGB1 can modulate osteoblast proliferation and migration is poorly understood, as well as the intracellular signalling pathways that are involved in this process.

[Regulation of biochar on matrix enzyme activities and microorganisms around cucumber roots under continuous cropping].

The effects of addition of biochar on the matrix enzymes activity, microorganisms population and microbial community structure were evaluated under cucumber continuous cropping for 6 years (11 rotations). Cucumbers were grown in pots in greenhouse with 5% or 3% of medium (by mass) substituted with biochar. The control consisted of medium alone without biochar.

CdSe/ZnS quantum dots based fluorescence quenching method for determination of paeonol.

Aqueous polymethylmethacrylate (PMMA)-capped CdSe/ZnS quantum dots were used as fluorescence probes for paeonol determination. Based on the fluorescence quenching of aqueous CdSe/ZnS quantum dots caused by paeonol, a simple, sensitive and rapid method was developed. Under the optimal conditions, with excitation and emission wavelengths at 350 nm and 620 nm, respectively, the calibration plot of F0-F with concentration of paeonol was linear in the range of 25.

[Statistical analysis of residues of heavy metals in Chinese crude drugs].

Objective: To analyze the residues of heavy metals in Chinese crude drugs.

Method: The SPSS 13.0 software was used to analyze the data of Cu, Pb, As, Cd, Hg collected in literatures.

[Composition and property characterization of Rhizoma Dioscoreae polysaccharide-Fe (III) complex].

Objective: To characterize properties of Rhizoma Dioscoreae polysaccharide-Fe (III) complex (RDPC) and analyze its composition.

Method: Physicochemical properties, such as character, solubility and stability of RDPC were studied. Surface structure of RDPC was studied by Infrared spectroscopic technique and transmission electron microscopy.

[Studies on chemical constituents of Dioscorea opposita].

Objective: To study the chemical constituents of Dioscorea opposita.

Method: The chemical constituents were isolated and purified by silica gel column chromatography, and the structures were elucidated by their spectroscopic data and physico-chemical properties.

Result: Twelve compounds were obtained and identified as palmitic acid (1), beta-sitosterol (2), oleic acid (3), beta-sitosterol acetate (4), 5-(hydroxymethyl)furfural (5), nonanedioic acid (6), beta-daucosterol (7), cyclo-(Phe-Tyr) (8), cyclo-(Tyr-Tyr) (9), 6-methyl citrate (10), 1, 5-dimethyl citrate (11), trimethyl citrate (12).

[Studies on flavonoid constituents from herbs of Artemisia ordosica II].

Objective: To study the chemical constituents of herbs of Artemisia ordosica.

Method: The chemical constituents were isolated and repeatedly purified on silica gel column and the structures were elucidated by the NMR spectra and physicochemical properties.

Result: Eight flavones were obtained and they were identified as isosakuranetin, 7, 4'-dimethylaro madendrin, acacetin, cirsimaritin, rhamnetin, eupatolin, 5, 7, 2', 4'-tetrahydroxy-6, 5'-dimethoxyflavone, hyperoside.

[Studies on chemical constituents of Acroptilon repens].

Objective: To investigate the chemical constituents of Acroptilon repens.

Method: The ethanol extract of A. repens was isolated and purified by means of chromatography.