Publications by authors named "Ming-Jie Song"
Diabetes-associated liver injury becomes a dominant hepatopathy, leading to hepatic failure worldwide. The current study was designed to evaluate the ameliorative effects of ginsenoside Rh1 (G-Rh1) on liver injury induced by T2DM. A T2DM model was established using C57BL/6 mice through feeding with HFD followed by injection with streptozotocin at 100 mg·kg.
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- The study examined the Schisandrae Chinensis Fructus at six growth stages to analyze changes in its composition, focusing on lignans, nucleosides, aroma components, and fatty acids using various chromatography techniques.
- Results indicated that the texture, color, and taste of the fruit varied across growth stages, with the highest total lignan content occurring from late August to early September and key compounds like schisandrin reaching 0.67%.
- Furthermore, the optimum harvesting period should align with the maturity stage to ensure the best quality and content of these compounds, providing valuable insights for quality evaluation of Schisandrae Chinensis Fructus.
Cisplatin (cis-Dichlorodiammine platinum, CP), as the first-line chemotherapy drug of choice for many cancers such as urogenital system tumors and digestive tract tumors, also causes toxicity and side effects to the kidney. Previous studies have shown that Pulsatilla chinensis has significant anti-inflammatory and antioxidant activities, but the mechanism of cisplatin induced acute kidney injury (AKI) in vivo has not been thoroughly studied. The purpose of this study is to investigate the protective effect of pulchinenoside B4 (PB4), a representative and major component with a content of up to 10% in root of P.
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