Publications by authors named "Ming-Hung Chung"
Article Synopsis
- This study highlights the importance of ongoing exercise for stroke patients to aid recovery and reduce medical costs.
- It tested a health management platform with wearable devices on stroke survivors, comparing its effectiveness to traditional care over 90 days with 26 participants.
- Results showed significant improvements in physical performance and self-management skills for the group using the platform, suggesting a need for continuous interaction between healthcare providers and patients using technology.
Cytoplasmic polyadenylation element binding protein 3 (CPEB3) is a sequence-specific RNA-binding protein that confines the strength of glutamatergic synapses by translationally downregulating the expression of multiple plasticity-related proteins (PRPs), including the N-methyl-D-aspartate receptor (NMDAR) and the postsynaptic density protein 95 (PSD95). CPEB3 knockout (KO) mice exhibit hippocampus-dependent abnormalities related not only to long-term spatial memory but also to the short-term acquisition and extinction of contextual fear memory. In this study, we identified a specific form of NMDAR-dependent synaptic depotentiation (DPT) that is impaired in the adult CPEB3 KO hippocampus.
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