Publications by authors named "Ming-Guo Dong"

Objective: To investigate the expressions of sarcoplasmic reticulum calcium ATPase 2a (SERCA2a) mRNA and miR-25-3p/5p in myocardium of rats with heart failure and the therapeutic effects of Xiefei Lishui recipe(Traditional Chinese Medicine).

Methods: SD rats were randomly divided into five groups:control group, model group, Traditional Chinese Medicine group(TCM group), captopril group and digoxin group(=10). Heart failure rat model was induced by intraperitoneal injections of doxorubicin(6 injections within 2 weeks; total dose:15 mg/kg).

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to investigate the levels of heat shock protein 70 (HSP70) antibodies in patients with cerebral infarction, especially those with hypertension, to understand their role in brain tissue damage.
  • One hundred patients were analyzed for HSP70 antibody levels using advanced testing techniques, with a comparison to healthy controls.
  • Results showed a significantly higher presence of HSP70 antibodies in cerebral infarction patients, particularly those with hypertension, suggesting that elevated HSP70 antibodies may correlate with the severity of brain damage.
View Article and Find Full Text PDF