[Medpor plus titanic mesh implant in the repair of orbital blowout fractures].

Objective: To study the efficacy of porous polyethylene (Medpor) plus titanic mesh sheets in the repair of orbital blowout fractures.

Methods: A total of 20 patients underwent open surgical reduction with the combined usage of Medpor and titanic mesh. And they were followed up for average period of 14.

[Estimation of preoperative corneal power in patients with myopic LASIK based on postoperative corneal data measured from Orbscan II].

Objective: Compare the change of pre- and post-operative posterior corneal curvature measurements in peripheral fitting zones using the Orbscan II topographer in patients undergoing myopic laser in situ keratomileusis (LASIK). To establish a new ratio of the anterior and posterior corneal curvature for the calculation of preoperative total corneal power using postoperative corneal data alone in patients after LASIK.

Methods: Retrospectively analyzed the changes of posterior corneal curvature in peripheral 7 to 10 mm fitting zones in 151 right eyes (151 individuals) 3 month after LASIK as measured by Orbscan II.

[Orbscan II-assisted intraocular lens power calculation after LASIK].

Objective: To evaluate the accuracy of keratometric value derived from one zone of Orbscan II mean power map after Laser in situ keratomileusis (LASIK) in combination with Holladay IOL Consultant software to calculate the intraocular lens (IOL) power.

Methods: A two-part study was conducted at a referral practice. Part 1 was a prospective study of 118 eyes undergoing LASIK.

Predicting protein-protein interactions from sequence using correlation coefficient and high-quality interaction dataset.

Identifying protein-protein interactions (PPIs) is critical for understanding the cellular function of the proteins and the machinery of a proteome. Data of PPIs derived from high-throughput technologies are often incomplete and noisy. Therefore, it is important to develop computational methods and high-quality interaction dataset for predicting PPIs.

TGFB1 as a susceptibility gene for high myopia: a replication study with new findings.

Objective: To investigate the genetic association between transforming growth factor beta1 (TGFB1) gene polymorphisms and high myopia in a Chinese population.

Methods: Six hundred adults were recruited for this case-control study, including 300 subjects with high myopia (-8.0 diopters or worse) and 300 control subjects (within +/-1.

[Exploration of three-dimensional biometric measurement of emmetropic adult eye-ball by using magnetic resonance imaging technology].

Objective: To study biometric measurements of emmetropic adult eyes with magnetic resonance imaging technology (MRI).

Method: MRI technology, with super-resolution, hyper-speed imaging and the integration of the thin-scanning layer, is applied to measure the three-dimensional biometric parameters of the eyeball. From January to December, 2003, emmetropic eyes from 31 normal Chinese adults (16 males and 15 females) aged from 18 to 32 years old (23.

A protein interaction network analysis for yeast integral membrane protein.

Although the yeast Saccharomyces cerevisiae is the best exemplified single-celled eukaryote, the vast number of protein-protein interactions of integral membrane proteins of Saccharomyces cerevisiae have not been characterized by experiments. Here, based on the kernel method of Greedy Kernel Principal Component analysis plus Linear Discriminant Analysis, we identify 300 protein-protein interactions involving 189 membrane proteins and get the outcome of a highly connected protein-protein interactions network. Furthermore, we study the global topological features of integral membrane proteins network of Saccharomyces cerevisiae.

[Studies of genetic polymorphism in retinopathy of prematurity].

Retinopathy of prematurity (ROP) is a vasoproliferative disease that happened in preterm infants with low gestational age and birth weight. Recently, many studies suggested that the incidence of ROP and the results of same clinical intervention vary between different races and countries. It seems that ROP may relate with genetic factors.

[A study on the mathematical model of normal adult cornea].

Objective: To explore the method on the conic equation to establish the mathematical model of the adult cornea and its preliminary result.

Methods: The curvature of anterior cornea and of posterior cornea, the corneal thickness of the points in the distance of 1.0, 1.

[To pay attention to the research and clinic application of the visual quality].

Superior visual quality not only means normal visual acuity, also includes normal contrast sensitivity, color vision, visual field and binocular vision. The concept of wave-front aberration and its correction technique have been introduced into the ophthalmology in China, and play an important role in finding and resolving the problems related to the visual quality. However, the concept and knowledge of the wave-front aberration does not get popularization in Chinese ophthalmologists.

[A study on the space form of the Schematic cornea of the normal adult eye-ball].

Objective: To detect the initial characters of the corneal shape that has been evaluated using a mathematical analysis.

Methods: Subjects were measured with Orbscan II corneal topography system. Anterior and posterior corneal radius of curvature and thickness of the points located 1.

[The grating acuity of children in preschool age].

Objective: To study the developmental trend of the binocular grating acuity of preschool children.

Methods: Binocular grating acuities in 599 children from 2 months to 72 months old (18 groups) were measured using the closed-circuit operant preferential looking system (COPLs). The children included in the investigation were required to be a normal term birth, development and normal eyes, and cycloplegic refraction error within specific limits.

[Design of a quantitative keratoscope used for ocular microsurgery].

A new quantitative keratoscope used specially for ocular microsurgery to measure corneal astigmatism is reported. A combined cylinder-lens, which power can be changed by rotating lens in anti-direction equally, was designed according to the principal of the crossing cylinder lens. The axis direction is fixed when the lens is rotated.

[The volume and dimensions of eyeball analyzed by MRI following encircling scleral buckles].

Objective: To assess the changes of the volume and dimensions of the eyeball and the vitreous following encircling scleral buckle.

Methods: 26 eyes from 26 patients received successful broad-band encircling scleral buckles for rhegmatogenous retinal detachment from July 2002 to December 2003. The examinations, A-scan ultrasonography (SONOMED A-5500, USA), Corneal topography and MRI, were performed preoperatively and at the first week postoperatively.