Surgical treatment of 42 patients with cerebral schistosomiasis caused by Schistosoma japonicum.

Objective: To investigate the clinical value of surgical treatment for cerebral schistosomiasis.

Methods: The clinical data of 42 patients with cerebral schistosomiasis caused by Schistosoma japonicum undergoing surgical therapy were analyzed retrospectively.

Results: There were 25 cases undergoing total resection of schistosomal granulomas and 17 cases undergoing partial resection of the lesions involving the functional areas or more than 2 lobes, and none died of the surgery.

[Preliminary study on establishing an animal model of neuroschistosomiasis by direct injection of Schistosoma japonicum eggs through skull].

Objective: To establish an experimental model of neuroschistosomiasis and investigate the model establishment factors.

Methods: Rabbits were used for the animal model and Schistosoma japonicum eggs (1 mg/ml) were directly injected into the brain by two ways of a bone drill or needle. The symptoms were observed and in the first and second week and later, the rabbits' brains were removed for pathological examinations.

Microsurgery Resection of Intrinsic Insular Tumors via Transsylvian Surgical Approach in 12 Cases.

Objective: To investigate the clinical characteristics, operative methods, and diffusion tensor imaging (DTI) in the resection of intrinsic insular gliomas via transsylvian approach.

Methods: From June 2008 to June 2010, 12 patients with intrinsic insular gliomas were treated via transsylvian microsurgical approach, with preoperative magnetic resonance imaging diffusion tensor imaging (MR DTI) evaluation. The data of these patients were retrospectively analyzed.

Establishment of a cerebral schistosomiasis experimental model in rabbits.

Objective: The present study aimed to establish a cerebral schistosomiasis model in rabbits, to provide a valuable tool for morphological analysis, clinical manifestation observation, as well as investigations into immunological reactions and pathogenesis of focal inflammatory reaction in neuroschistosomiasis (NS).

Methods: Sixty New Zealand rabbits were randomly assigned into operation, sham-operation and normal groups. Rabbits in the operation group received direct injection of dead schistosome eggs into the brain, while their counterparts in the sham-operation group received saline injection.

Research development of the pathogenesis pathways for neuroschistosomiasis.

The infection of the central nervous system (CNS) by schistosome may or may not have clinical manifestations. When symptomatic, neuroschistosomiasis (NS) is one of the most severe presentations of schistosome infection. Among the NS symptoms, cerebral invasion is mostly caused by Schistosoma japonicum (S.

[Surgical treatment of patients with cerebral schistosomiasis].

Clinical data from 48 cases with cerebral schistosomiasis, who received surgery, were analyzed retrospectively. Surgical treatment was performed when the patient had the following conditions: mass focus confirmed by CT scanning, cranial hypertension, or ineffective drug therapy, or indistinguishable from glioma by iconographic diagnosis. Treatment of praziquantel was given when the patients got improved.

Rapid natural resolution of intracranial hematoma.

Objective: To investigate the clinical characteristics of intracranial hematoma and the mechanism involved in its rapid natural resolution.

Methods: Seventeen cases of intracranial hematoma with typical clinical and CT manifestations were retrospectively studied.

Results: Intracranial hematoma was found obviously decreased in size within 72 h after its occurrence in 8 cases.