Publications by authors named "Ming-Bo Gao"
Objective: We aimed to investigate the effect of Lycium barbarum polysaccharide (LBP) on the proliferation and differentiation of osteoblasts in postmenopausal individuals with osteoporosis using in vitro cell experiments.
Methods: We assessed the effect of long-term LBP consumption on the intestinal metabolites of individuals using a simulation of the human intestinal microbiota ecosystem. We also tested the capacity of LBP in proliferating MC3T3-E1 cells using the cell counting kit-8 (CCK-8) method and analyzed the effect of intestinal metabolites on the osteogenic differentiation of MC3T3-E1 cells by testing bone metabolism viability with relevant indicators.
Article Synopsis
- - The study investigates the protective effects of Astragalus polysaccharides (APS) on mitochondria and its potential anti-aging activities, particularly how it counters lipid peroxidation in liver and brain mitochondria caused by Fe(2+)-Vit C.
- - Methods like TBA colorimetry and spectrophotometry were used to measure oxidative damage and mitochondrial permeability, while APS demonstrated significant scavenging of harmful free radicals such as superoxide anion and hydroxyl radicals in a concentration-dependent manner.
- - In vivo experiments using mice showed that APS could enhance the activity of key antioxidant enzymes (catalase, superoxide dismutase, and glutathione peroxidase) and inhibit damaging processes, indicating its potential
Cordyceps militaris (L.) Link is an entomopathogenic fungus parasitic to Lepidoptera larvae, and is widely used as a folk tonic or invigorant for longevity in China. Although C.
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