Influence maximization in multilayer networks based on adaptive coupling degree.

Influence maximization (IM) aims to identify highly influential nodes to maximize influence spread in a network. Previous research on the IM problem has mainly concentrated on single-layer networks, disregarding the comprehension of the coupling structure that is inherent in multilayer networks. To solve the IM problem in multilayer networks, we first propose an independent cascade model (MIC) in a multilayer network where propagation occurs simultaneously across different layers.

Remote sensing of the oil spills caused by ships: A review.

Oil spills caused by ships can be categorized as accidental and operational oil spills. For operational oil spills caused by illegal discharge, an efficient remote sensing system for routine surveillance on oil spills needs to be established. For the oil spills caused by ship accidents, the quantitative inversion on some key properties provides useful information for treatment and assessment.

UBE2T/CDC42/CD276 signaling axis mediates brain metastasis of triple-negative breast cancer via lysosomal autophagy.

Background: Advanced triple-negative breast cancer (TNBC) is prone to brain metastasis (BrM). The precise molecular mechanism responsible for this phenomenon has not yet been completely established, so it is vital to comprehend the molecular mechanism behind it.

Methods: The protein chip analysis was conducted to identify any abnormal UBE2T protein expression in TNBC, especially BrM.

Detecting living microalgae in ship ballast water based on stained microscopic images and deep learning.

Motivated by the need of rapid detection of living microalgae cells in ship ballast water, this study is intended to determine the activities of microalgae using stained microscopic images and detect the living cells with image processing algorithms. The staining selectivity on living cells of neutral red dye is utilized to distinguish the activities of microalgae. A deep-learning-based detection model was designed and tested using the microscopic images of stained microalgae cells.

Development of a nomogram model to predict postoperative urinary retention risk after transabdominal preperitoneal inguinal hernia repair.

Objective: To explore independent risk factors and to establish a predictive model for postoperative urinary retention (POUR) following transabdominal preperitoneal inguinal hernia repair (TAPP).

Methods: Between January 2017 and December 2023, 598 patients with inguinal hernia who underwent TAPP at the General Surgery Department of Zunyi Medical University Affiliated Liupanshui Hospital were enrolled in the study. Participants were randomly divided into training and validation sets (7:3 ratio).

Transanal vs Laparoscopic Total Mesorectal Excision and 3-Year Disease-Free Survival in Rectal Cancer: The TaLaR Randomized Clinical Trial.

Importance: Previous studies have demonstrated the advantages of short-term histopathological outcomes and complications associated with transanal total mesorectal excision (TME) compared with laparoscopic TME. However, the long-term oncological outcomes of transanal TME remain ambiguous. This study aims to compare 3-year disease-free survival of transanal TME with laparoscopic TME.

Environmental Catalysis for NO Reduction by Manipulating the Dynamic Coordination Environment of Active Sites.

Nowadays, it is challenging to achieve SO-tolerant environmental catalysis for NO reduction because of the thermodynamically favorable transformation of reactive sites to inactive sulfate species in the presence of SO. Herein, we achieve enhanced low-temperature SO-tolerant NO reduction by manipulating the dynamic coordination environment of active sites. Engineered by coordination chemistry, SiO-CeO composite oxides with a short-range ordered Ce-O-Si structure were elaborately constructed on a TiO support.

First-line cadonilimab plus chemotherapy in HER2-negative advanced gastric or gastroesophageal junction adenocarcinoma: a randomized, double-blind, phase 3 trial.

Programmed cell death protein-1 (PD-1) inhibitors plus chemotherapy have been the standard of care in the first-line treatment of advanced gastric or gastroesophageal junction (G/GEJ) adenocarcinoma; however, the survival benefits are modest in patients with low programmed death ligand 1 (PD-L1) expression. Here we investigated the efficacy and safety of cadonilimab (PD-1/cytotoxic T lymphocyte antigen-4 (CTLA-4) bispecific antibody) plus chemotherapy as first-line treatment in G/GEJ adenocarcinoma. The prespecified interim analysis is reported here.

Effect of Nutritional Intervention on Chemotherapy Tolerance and Quality of Life in Patients with Colorectal Cancer Undergoing Postoperative Chemotherapy: A Randomized Controlled Study.

This study explored the effect of symptom-based individualized nutritional intervention on chemotherapy tolerance and quality of life (QOL) in patients with colorectal cancer (CRC) undergoing postoperative chemotherapy. Postoperative patients with CRC ( = 88) were randomly assigned to the control group (CG,  = 45) and intervention group (IG,  = 43) receiving conventional diet counseling and symptom-based individualized nutritional intervention, respectively, and chemotherapy tolerance, adverse effects, and QOL were compared. Participants in the IG exhibited better nutritional status at the last chemotherapy cycle, with lower Nutrition Risk Screening 2002 (2.

Mix-Charged Nanofiltration Membrane for Efficient Organic Removal from High-Salinity Wastewater: The Role of Charge Spatial Distribution.

The efficient removal of organic contaminants from high-salinity wastewater is crucial for resource recovery and achieving zero discharge. Nanofiltration (NF) membranes are effective in separating organic compounds and monovalent salts, but they typically exhibit an excessive rejection of divalent salts. Modifying the charge characteristics of NF membranes can improve salt permeation; however, the role of charge spatial distribution in governing salt transport behavior is not fully understood.

Host lipid metabolism influences the variation in resistance of Pekin ducks to duck hepatitis A virus genotype 3.

Duck viral hepatitis (DVH) is a common and serious acute infectious disease that has a significantly impact on the duck farming industry. Duck hepatitis A virus type 3 (DHAV-3) is the major causative agent of DVH in East Asia. Host factor indicators of resistance to DHAV-3 in Pekin ducks were investigated using resistant (Z7R) and susceptible (Z7S) duck lines.

The crosstalks between vascular endothelial cells, vascular smooth muscle cells, and adventitial fibroblasts in vascular remodeling.

Pathological vascular remodeling (VR) is characterized by structural and functional alterations in the vascular wall resulting from injury, which significantly contribute to the development of cardiovascular diseases (CVDs). The vascular wall consists primarily of endothelial cells (ECs), vascular smooth muscle cells (VSMCs), and adventitial fibroblasts (AFs), whose interactions are crucial for both the formation of the vascular system and the maintenance of mature blood vessels. Disruptions in the communication between these cell types have been implicated in the progression of VR.

Gut Microbiota and Metabolite Profiles Associated With Functional Constipation Severity.

Functional constipation (FC) is a common digestive disorder that affects patients' quality of life and is closely associated with intestinal tumors. This study used a cross-sectional design to assess the changes of intestinal flora and metabolites in different severities of FC patients through 16S rRNA sequencing and metabolomics analysis. Results showed that patients with severe FC had significantly higher clinical and anxiety scores compared to those in the mild and moderate groups.

Feature genes identification and immune infiltration assessment in abdominal aortic aneurysm using WGCNA and machine learning algorithms.

Objective: Abdominal aortic aneurysm (AAA) is a life-threatening vascular condition. This study aimed to discover new indicators for the early detection of AAA and explore the possible involvement of immune cell activity in its development.

Methods: Sourced from the Gene Expression Omnibus, the AAA microarray datasets GSE47472 and GSE57691 were combined to generate the training set.

A YOLO-Based Method for Head Detection in Complex Scenes.

Detecting objects in intricate scenes has always presented a significant challenge in the field of machine vision. Complex scenes typically refer to situations in images or videos where there are numerous densely distributed and mutually occluded objects, making the object detection task even more difficult. This paper introduces a novel head detection algorithm, YOLO-Based Head Detection in Complex Scenes (YOLO-HDCS).

Vitamin D requirements and relative bioavailability for starter male White Pekin ducks fed either cholecalciferol or 25-hydroxycholecalciferol.

The objectives were to investigate effects of various concentrations of dietary vitamin D (VD) or 25-hydroxycholecalciferol (25-OH-D) on growth performance, VD status, calcium (Ca) metabolism, and tibia mineralization of starter male White Pekin ducks, and dietary requirements and relative bioavailability of these two compounds. One-day-old male White Pekin ducks (n = 624) were assigned to 13 dietary treatments, including 6 added VD concentrations (100, 200, 400, 800, 1200, and 2000 IU/kg), and 2 vitamin D sources (VD and 25-OH-D), plus a negative control (no vitamin D supplementation) for 21 days. Each group had 6 replicate pens of 8 birds per pen.

Radiomics based on brain-to-tumor interface enables prediction of metastatic tumor type of brain metastasis: a proof-of-concept study.

Background: Early and accurate identification of the metastatic tumor types of brain metastasis (BM) is essential for appropriate treatment and management.

Methods: A total of 450 patients were enrolled from two centers as a primary cohort who carry 764 BMs originated from non-small cell lung cancer (NSCLC, patient = 173, lesion = 187), small cell lung cancer (SCLC, patient = 84, lesion = 196), breast cancer (BC, patient = 119, lesion = 200), and gastrointestinal cancer (GIC, patient = 74, lesion = 181). A third center enrolled 28 patients who carry 67 BMs (NSCLC = 24, SCLC = 22, BC = 10, and GIC = 11) to form an external test cohort.

The activation of SYNJ2/GRB2 axis accelerates the malignant metastasis and angiogenesis of gastric cancer cells.

In gastric cancer (GC), tumor cell metastasis to lymph node may occur, and can be impacted by synaptojanin 2 (SYNJ2). Herein, we explored the mechanism of SYNJ2 in the progress of GC. SYNJ2 level in GC tissues was predicted by GEPIA database.

Long-Lived Topological Flatband Excitons in Semiconductor Moiré Heterostructures: A Bosonic Kane-Mele Model Platform.

Moiré superlattices based on two-dimensional transition metal dichalcogenides (TMDs) have emerged as a highly versatile and fruitful platform for exploring correlated topological electronic phases. One of the most remarkable examples is the recently discovered fractional quantum anomalous Hall effect (FQAHE) under zero magnetic field. Here, we propose a minimal structure that hosts long-lived excitons-a ubiquitous bosonic excitation in TMD semiconductors-with narrow topological bosonic bands.

Molecular regulation by HS of antioxidant and glucose metabolism in cold-sensitive Capsicum.

Background: Cold is an important environmental limiting factor affecting plant yield and quality. Capsicum (chili pepper), a tropical and subtropical vegetable crop, is extremely sensitive to cold. Although HS is an important signaling regulator in the responses of plant growth and development to abiotic stress, few studies have examined its effects on cold-sensitive capsicum varieties.

Sarcopenia Predicts Postoperative Complications and Survival of Colorectal Cancer Patients Undergoing Radical Surgery.

Previous literature has indicated that sarcopenia is related to poor outcomes after radical resection for colorectal cancer (CRC). However, its effect on the postoperative clinical outcomes of CRC remains controversial. This study aimed to elucidate the predictive value of sarcopenia for postoperative complications and survival in CRC patients.