Use of sulfated cyclofructan 6 and sulfated cyclodextrins for the chiral separation of four basic pharmaceuticals by capillary electrophoresis.

Sulfated cyclofructan 6 (S-CF6) and sulfated cyclodextrins (S-α-, β-, γ-CDs) are highly selective chiral selectors for the enantioseparation of basic solutes. In this study, S-CF6 was introduced for the enantiomeric separation of four basic pharmaceuticals (including tamsulosin, tiropramide, bupivacaine, and norephedrine) by capillary electrophoresis (CE), and the enantiomeric separation performance was compared with S-α-, β-, γ-CDs. The effects of the chiral selector type, chiral selector concentration, operating voltage, and column temperature were examined and optimized.

A novel method to prepare monolithic molecular imprinted polymer fiber for solid-phase microextraction by microwave irradiation.

In this paper, a new approach to prepare monolithic molecularly imprinted polymer (MIP) fibers for solid-phase microextraction is proposed with the help of microwave irradiation. Imprinting polymerization was carried out within silica capillaries in 4.5 min, using dimethyl phthalate (DMP) as a template molecular, α-methacrylic acid as a functional monomer and ethylene dimethacrylate as a crosslinker, acetonitrile as the porogenic solvent.

[A preliminary study of maxillary reconstruction using free fibula-flexor hallucis longus myofascial flap].

Objective: To analyze the rationale and feasibility of maxillary reconstruction using free fibula-flexor hallucis longus myofascial flap.

Methods: Nine consecutive cases of maxillary reconstruction using free fibula-flexor hallucis longus myofascial flaps from August of 2002 to August of 2003 were reviewed. Data concerning the operation included description of maxillary defect, design of the fibula flaps, recipient vessel and complications.