Molecular Copper-Anthraquinone Photocatalysts for Robust Hydrogen Production.

The development of robust and inexpensive photocatalysts for H production under visible light irradiation remains a significant challenge. This study presents a series of square planar copper anthraquinone complexes (RN)CuL (R = ethyl, L = alizarin dianion (CuAA); R = -butyl, L = purpurin dianion (CuPP), (2-hydroxyanthraquinone)formamide dianion (CuAHA)) as molecular photocatalysts to achieve high long-term stability in visible-light-driven H production. These complexes are self-sensitized by the anthraquinone ligands and serve as proton reduction photocatalysts without additional photosensitizers or catalysts.

Fluorinated chlorin chromophores for red-light-driven CO reduction.

The utilization of low-energy photons in light-driven reactions is an effective strategy for improving the efficiency of solar energy conversion. In nature, photosynthetic organisms use chlorophylls to harvest the red portion of sunlight, which ultimately drives the reduction of CO. However, a molecular system that mimics such function is extremely rare in non-noble-metal catalysis.

Identification of a signature of histone modifiers in kidney renal clear cell carcinoma.

Kidney renal clear cell carcinoma (KIRC) is a cancer that is closely associated with epigenetic alterations, and histone modifiers (HMs) are closely related to epigenetic regulation. Therefore, this study aimed to comprehensively explore the function and prognostic value of HMs-based signature in KIRC. HMs were first obtained from top journal.

Pyridinethiolate-Capped CdSe Quantum Dots for Red-Light-Driven H Production in Water.

The utilization of low-energy sunlight to produce renewable fuels is a subject of great interest. Here we report the first example of metal chalcogenide quantum dots (QDs) capped with a pyridinethiolate carboxylic acid (pyS-COOH) for red-light-driven H production in water. The precious-metal-free system is robust over 240 h, and achieves a turnover number (TON) of 43910±305 (vs Ni) with a rate of 31570±1690 μmol g h for hydrogen production.

Preparation and Mechanical Properties of Core-Shell PS&CeO Composite Abrasive Particles.

Core-shell composite abrasive particles are a topic of great interest in surface finishing. It is important to explore the preparation technology and performance parameters associated with them. In this paper, a core-shell composite abrasive particle made of polystyrene and cerium oxide (PS&CeO, CSPC), which is rigid on the outside and flexible on the inside, is proposed.

Deep learning of heart-sound signals for efficient prediction of obstructive coronary artery disease.

Background: Due to the limitations of current methods for detecting obstructive coronary artery disease (CAD), many individuals are mistakenly or unnecessarily referred for coronary angiography (CAG).

Objectives: Our goal is to create a comprehensive database of heart sounds in CAD and develop accurate deep learning algorithms to efficiently detect obstructive CAD based on heart sound signals. This will enable effective screening before undergoing CAG.

Gain enhancement of perovskite nanosheets by a patterned waveguide: excitation and temperature dependence of gain saturation.

Optical gain enhancement of two-dimensional CsPbBr nanosheets was studied when the amplified spontaneous emission is guided by a patterned structure of polyurethane-acrylate. Given the uncertainties and pitfalls in retrieving a gain coefficient from the variable stripe length method, a gain contour [Formula: see text] was obtained in the plane of spectrum energy (ℏω) and stripe length (x), whereby an average gain was obtained, and gain saturation was analysed. Excitation and temperature dependence of the gain contour show that the waveguide enhances both gain and thermal stability due to the increased optical confinement and heat dissipation, and the gain origins were attributed to the two-dimensional excitons and the localized states.

Autophagy regulates tumor growth and metastasis.

The role of autophagy in tumorigenesis and tumor metastasis remains poorly understood. Here we show that inhibition of autophagy stabilizes the transcription factor Twist1 through Sequestosome-1 (SQSTM1, also known as p62) and thus increases cell proliferation, migration, and epithelial-mesenchymal transition (EMT) in tumor development and metastasis. Inhibition of autophagy or p62 overexpression blocks Twist1 protein degradation in the proteasomes, while p62 inhibition enhances it.

Identification of a Novel Myc-Regulated Gene Signature for Patients with Kidney Renal Clear Cell Carcinoma.

Given that myc was known to be a cancer-causing gene in several cancers including kidney renal clear cell carcinoma (KIRC). We aimed to construct myc-regulated genes (MRGs)-based prognostic signature. We obtained the mRNA expression and clinical data of KIRC from The Cancer Genome Atlas (TCGA) database and MRGs from the Molecular Signature Database (MSigDB).

Photocatalytic CO reduction with aminoanthraquinone organic dyes.

The direct utilization of solar energy to convert CO into renewable chemicals remains a challenge. One essential difficulty is the development of efficient and inexpensive light-absorbers. Here we show a series of aminoanthraquinone organic dyes to promote the efficiency for visible light-driven CO reduction to CO when coupled with an Fe porphyrin catalyst.

Optical Gain of Vertically Coupled CdZnTe/ZnTe Quantum Dots.

The optical modal gain of CdZnTe/ZnTe double quantum dots was measured using a variable stripe length method, where large and small quantum dots are separated with a ZnTe layer. With a large (~18 nm) separation layer thickness of ZnTe, two gain spectra were observed, which correspond to the confined exciton levels of the large and small quantum dots, respectively. With a small (~6 nm) separation layer thickness of ZnTe, a merged single gain spectrum was observed.

Molecular Nickel Thiolate Complexes for Electrochemical Reduction of CO to C Hydrocarbons.

We report the unprecedented electrocatalytic activity of a series of molecular nickel thiolate complexes (1-5) in reducing CO to C hydrocarbons on carbon paper in pH-neutral aqueous solutions. Ni(mpo) (3, mpo=2-mercaptopyridyl-N-oxide), Ni(pyS) (4, pyS=2-mercaptopyridine), and Ni(mp) (5, mp=2-mercaptophenolate) were found to generate C products from CO for the first time in molecular complex. Compound 5 exhibits Faradaic efficiencies (FEs) of 10.

Bionic structure and blood compatibility of highly oriented homo-epitaxially crystallized poly(l-lactic acid).

A highly oriented poly(l-lactic acid) (PLLA), with a blood vessel-like biomimetic structure, was fabricated using solid-phase hot drawing technology and homo-epitaxial crystallization to improve the mechanical properties and biocompatibility of PLLA. Long chain branched PLLA (LCB-PLLA) was prepared through a two-step ring-opening reaction, and a consequent draw as high as 1000 % was achieved during the hot drawing. The modulus and tensile strength were found to have increased through the formation of oriented shish-kebab like crystals along the drawing direction during processing.

Efficient Red-Light-Driven Hydrogen Evolution with an Anthraquinone Organic Dye.

The direct utilization of the full solar spectrum to obtain renewable fuels remains a challenge because the conversion of the low-energy light (red and near-infrared) is difficult. Current light-driven systems show activity for hydrogen generation with the high-energy part of sunlight. Here we report the use of a simple anthraquinone organic dye in an artificial photosynthetic system that promotes efficient red-light-driven production of hydrogen.

Improving Photocatalytic Hydrogen Production through Incorporating Copper to Organic Photosensitizers.

Organic dyes have been investigated extensively as promising photosensitizers in noble-metal-free photocatalytic systems for hydrogen production. However, other than functional group optimization, there are very few methods reported to be effective in improving their photocatalytic activity. Herein, we report the incorporation of Cu into purpurin and gallein dyes for visible-light-driven hydrogen production.

Combination of Organic Dye and Iron for CO Reduction with Pentanuclear FeNa Purpurin Photocatalysts.

Molecular photocatalysts designed with earth-abundant elements are rare and challenging in artificial photosynthesis study. Herein, we report a multimetallic FeNa purpurin () complex for the reduction of CO in DMF under visible-light irradiation. The photocatalytic system achieves 91% selectivity and 2625 ± 334 turnovers of CO in 120 h, which is among the highest reported for a noble-metal-free catalyst without an additional photosensitizer.

Selective perrhenate/pertechnetate removal by a MOF-based molecular trap.

A rational design of anion-exchange materials for the selective elimination of radioactive anionic contaminants poses a great challenge. Rather than relying on a size-compatible effect, the combination of a nano-sieve pore, hydrophobic cationic cavity, and soft-acidic open metal sites within one sorbent is an emerging strategy for meeting the requirement. Here, we designed a porous cationic Ag(I) metal-organic framework (MOF), TNU-132, which combined multiple features and showed superior perrhenate/pertechnetate capture selectivity in the presence of a large excess of 300-fold NO and 2000-fold SO.

Low-dose oral hydroxychloroquine led to impaired vision in a child with renal failure: Case report and literature review.

Introduction: Hydroxychloroquine (HCQ) has received much attention in the treatment of coronavirus disease 2019 recently. However, it can cause irreversible vision loss. Few cases have been reported in pediatric patient with HCQ-related adverse reactions.

Inhibition of B-cell receptor signaling disrupts cell adhesion in mantle cell lymphoma via RAC2.

Inhibition of the B-cell receptor (BCR) signaling pathway is highly effective in B-cell neoplasia through Bruton tyrosine kinase inhibition by ibrutinib. Ibrutinib also disrupts cell adhesion between a tumor and its microenvironment. However, it is largely unknown how BCR signaling is linked to cell adhesion.

Uniformly distributed ruthenium nanocrystals as highly efficient peroxidase for hydrogen peroxide colorimetric detection and nitroreductase for 4-nitroaniline reduction.

Here, we report highly dispersed small ruthenium nanoparticles (NPs) anchored onto a porous carbon (Ru/PC) with a clean catalytic surface and explore their excellent peroxidase-like activity for 3,3',5,5'-tetramethylbenzidine oxidation mediated by HO, which allows sensitive colorimetric detection of HO with a low detection limit of 3.8 μM. Moreover, it is also found that the Ru/PC has a high nitroreductase-like activity for 4-nitroaniline reduction triggered by NaBH.

Room-Temperature Sustainable Synthesis of Selected Platinum Group Metal (PGM = Ir, Rh, and Ru) Nanocatalysts Well-Dispersed on Porous Carbon for Efficient Hydrogen Evolution and Oxidation.

Electroless deposition via a spontaneous redox reaction between the metal precursor and support is believed to be a promising approach for the syntheses of supported metal nanoparticles (SMNPs). However, its widespread applications are significantly prohibited by the low reductivity and high cost of support. To overcome these shortcomings, a porous carbon (PC) is herein developed as a promising matrix for the electroless deposition of metal NPs.

Learning face perception without vision: Rebound learning effect and hemispheric differences in congenital vs late-onset blindness.

To address the longstanding questions of whether the blind-from-birth have an innate face-schema, what plasticity mechanisms underlie non-visual face learning, and whether there are interhemispheric face processing differences in face processing in the blind, we used a unique non-visual drawing-based training in congenitally blind (CB), late-blind (LB) and blindfolded-sighted (BF) groups of adults. This Cognitive-Kinesthetic Drawing approach previously developed by Likova (e.g.

Effects of Siniruangan Recipe on Proliferation, Apoptosis and Activation of Human Hepatic Stellate Cell Line LX-2.

Background: Experimental and clinical evidence suggests that liver fibrosis is potentially reversible. Hepatic stellate cells (HSCs) play a key role in the development of hepatic fibrosis. Previous clinical applications and researches showed that Siniruangan recipe (SNRG) reversed liver fibrosis and even liver cirrhosis.