Publications by authors named "Ming May Chung"
Article Synopsis
- * The interaction between inducible T-cell co-stimulator ligand (ICOS-L) and its receptor (ICOS) is essential for immunofibroblasts to produce LTα3, which promotes the production of chemokines necessary for TLS formation.
- * Blocking the ICOS/ICOS-L interaction leads to reduced LTα expression and hinders TLS development, highlighting the immunomodulatory capabilities of immunofibroblasts and their importance in maintaining TLS in both mice and humans.
Lymphangiogenesis associated with tertiary lymphoid structure (TLS) has been reported in numerous studies. However, the kinetics and dynamic changes occurring to the lymphatic vascular network during TLS development have not been studied. Using a viral-induced, resolving model of TLS formation in the salivary glands of adult mice we demonstrate that the expansion of the lymphatic vascular network is tightly regulated.
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