Publications by authors named "Mine S"

Terahertz (THz) parametric detection is a highly sensitive method that upconverts a THz wave into a near-infrared beam for detection. Lithium niobate has primarily been used as the nonlinear optical crystal in this approach. However, the frequency band with high parametric gain is limited, leading to increasing interest in other nonlinear optical crystals.

View Article and Find Full Text PDF

Microthrombus formation is associated with COVID-19 severity; however, the detailed mechanism remains unclear. In this study, we investigated mouse models with severe pneumonia caused by SARS-CoV-2 infection by using our in vivo two-photon imaging system. In the lungs of SARS-CoV-2-infected mice, increased expression of adhesion molecules in intravascular neutrophils prolonged adhesion time to the vessel wall, resulting in platelet aggregation and impaired lung perfusion.

View Article and Find Full Text PDF
Article Synopsis
  • The study focuses on the tumor immune microenvironment, particularly the roles of regulatory T cells (Tregs) and cytotoxic T cells (CD8+), as factors influencing prognosis in aggressive gastroesophageal adenocarcinomas (GEAs).
  • It found that a high FOXP3+/CD8+ cell ratio at the invasive margin of tumors correlates with worse survival outcomes, especially in RUNX3-methylated diffuse variants compared to intestinal types.
  • The research suggests that increased FOXP3+/CD8+ ratios may facilitate immune evasion in tumors, potentially linked to the signaling molecule CCL28 and its relationship with RUNX3 methylation status.
View Article and Find Full Text PDF

d-Allulose is a low-calorie sweetener with multiple nutritional functions that can be produced through d-fructose isomerization by ketose 3-epimerase (KEase). l-Ribulose 3-epimerase from Arthrobacterglobiformis (AgLRE) is one of the most important enzymes that produce d-allulose; however, its substrate recognition mechanism is unknown. In this study, the crystal structures of AgLRE and its complex with d-allulose and d-fructose were determined.

View Article and Find Full Text PDF

Technological enablers that use CO as a feedstock to create value-added chemicals, including ethanol, have gained widespread appeal. They offer a potential solution to climate change and promote the development of a circular economy. However, the conversion of CO to ethanol poses significant challenges, not only because CO is a thermodynamically stable and chemically inert molecule but also because of the complexity of the reaction routes and uncontrollability of C-C coupling.

View Article and Find Full Text PDF
Article Synopsis
  • Intrathoracic herniation of the gastric tube following oesophagectomy is uncommon but can often be treated conservatively.
  • The report focuses on two patients who required surgery due to this herniation after minimally invasive oesophagectomy for esophageal cancer, highlighting complications like ischemia and delayed gastric emptying.
  • The discussion includes the reasons for herniation, criteria for surgical intervention, and strategies to prevent this complication in the future.
View Article and Find Full Text PDF

Catalytic propane dehydrogenation (PDH) has mainly been studied using metal- and metal oxide-based catalysts. Studies on dehydrogenation catalysis by metal hydrides, however, have rarely been reported. In this study, PDH reactions using group IIIB and IVB metal hydride catalysts were investigated under relatively low-temperature conditions of 450 °C.

View Article and Find Full Text PDF
Article Synopsis
  • Numerous antibody biomarkers exist for cancer and atherosclerosis-related diseases, highlighting the connections between conditions like acute ischemic stroke, cardiovascular disease, and diabetes mellitus.
  • The study identifies KIAA0513 as a potential common biomarker linked to these diseases, showing higher serum antibody levels in patients compared to healthy individuals.
  • The research suggests that serum anti-KIAA0513 antibody levels could effectively diagnose various conditions, indicating shared arterial changes associated with both atherosclerosis and cancer.
View Article and Find Full Text PDF
Article Synopsis
  • The study analyzed 5804 days of Super-Kamiokande data from 1996 to 2018 to detect variations in solar ^{8}B neutrino flux.
  • The researchers utilized a five-day interval measurement approach and employed maximum likelihood and Lomb-Scargle methods to find any periodic modulations.
  • They found a significant modulation related to Earth's elliptical orbit around the Sun, with measurements of eccentricity and perihelion shift aligning with astronomical data.
View Article and Find Full Text PDF

In this review, we summarize the modifications made in the Japanese Classification of Esophageal Cancer 12th edition, identify several issues, and discuss the prospects for the next 13th edition.

View Article and Find Full Text PDF

Postoperative pneumothorax is a well-known but relatively rare complication after laparoscopic surgery. Herein, we report a case of persistent pneumothorax after laparoscopic appendectomy. A 57-year-old male, with a history of minimally invasive esophagectomy and intrathoracic gastric tube reconstruction 5 years before, underwent a laparoscopic appendectomy.

View Article and Find Full Text PDF

Inflammation is closely associated with cerebrovascular diseases, cardiovascular diseases, diabetes, and cancers, and it is accompanied by the development of autoantibodies in the early stage of inflammation-related diseases. Hence, it is meaningful to discover novel antibody biomarkers targeting inflammation-related diseases. In this study, Jumonji C-domain-containing 6 (JMJD6) was identified by the serological identification of antigens through recombinant cDNA expression cloning.

View Article and Find Full Text PDF

This is the first half of English edition of Japanese Classification of Esophageal Cancer, 12th Edition that was published by the Japan Esophageal Society in 2022.

View Article and Find Full Text PDF

This is the second half of English edition of Japanese Classification of Esophageal Cancer, 12th Edition that was published by the Japan Esophageal Society in 2022.

View Article and Find Full Text PDF

Adult-onset intussusception, particularly associated with colonoscopy, is extremely rare. A 78-year-old man, referred to our hospital for colonic endoscopic mucosal resection (EMR), experienced subsequent dull abdominal pain, as well as elevated peripheral blood leukocytosis and C-reactive protein levels. Abdominal computed tomography (CT) revealed a colocolonic intussusception at the hepatic flexure.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluated the LC16m8 vaccine's safety and effectiveness against the monkeypox virus (MPXV) in 50 healthy adults over 168 days.
  • On day 28, the vaccine showed strong immunogenicity, with 72% to 88% seroconversion rates, although these rates declined by day 168.
  • Adverse events were common but mostly mild, and no serious safety issues or cases of monkeypox were reported during the study period.
View Article and Find Full Text PDF

Waste beverages are utilized as resources in various valuable, albeit energy-consuming, waste-to-energy processes. There is a growing need for alternative cost-effective methods to harness their potential. This study explored the feasibility of employing waste beverages as feedstock for the counterpart component of a TiO-based composite photocatalyst.

View Article and Find Full Text PDF

Single-atom catalysts are thought to be the pinnacle of catalysis. However, for many reactions, their suitability has yet to be unequivocally proven. Here, we demonstrate why single Pd atoms (Pd) are not catalytically ideal for generating H from formic acid as a H carrier.

View Article and Find Full Text PDF

Gastrointestinal stromal tumors (GISTs) are typically characterized by activating mutations of the KIT proto-oncogene receptor tyrosine kinase (KIT) or platelet-derived growth factor receptor alpha (PDGFRA). Recently, the neurotrophic tyrosine receptor kinase (NTRK) fusion was reported in a small subset of wild-type GIST. We examined trk IHC and NTRK gene expressions in GIST.

View Article and Find Full Text PDF

Resilin is an elastic protein that is vital to insects' vigorous movement. Canonical resilin proteins possess the R&R Consensus, a chitin-binding domain conserved in a family of cuticular proteins, and highly repetitive sequences conferring elastic properties. In the malaria vector mosquito, , however, a cuticular protein has been found that has an R&R Consensus resembling that of resilin but lacks the repetitive sequences (here, we call it resilin-related or resilin-r).

View Article and Find Full Text PDF

Objective: Ictal direct current shifts (icDCs) and ictal high-frequency oscillations (icHFOs) have been reported as surrogate markers for better surgical outcomes in epilepsy surgery. icDCs have been classified into two types: rapid and slow development. icDCs have been investigated with a time constant of 10 s (TC10s); however, many institutes use electroencephalography with a time constant of 2 s (TC2s).

View Article and Find Full Text PDF

Background: Autoantibodies develop in autoimmune diseases, cancer, diabetes mellitus (DM), and atherosclerosis-related diseases. However, autoantibody biomarkers have not been successfully examined for diagnosis and therapy.

Methods: Serological identification of antigens through recombinant cDNA expression cloning (SEREX) was used for primary screening of antigens.

View Article and Find Full Text PDF