Characteristics of women with gynecologic cancer who enter clinical trials.

Objective: To determine if differences exist between gynecologic cancer patients who participate in clinical trials and those who do not.

Study Design: Two hundred thirty-six subjects with gynecologic cancer diagnosed between 1997 and 2001 were identified. Multiple clinical and demographic factors, including clinical trial enrollment, postoperative treatment and related complications, were recorded.

The predictive value of cytologic testing in women with the human immunodeficiency virus who have low-grade squamous cervical lesions: a substudy of a randomized, phase III chemoprevention trial.

Objective: The purpose of this study was to determine whether the progression of low-grade squamous intraepithelial lesions of the cervix in women with the human immunodeficiency virus can be predicted reliably by standard cytologic testing.

Study Design: As part of a previously reported trial, 288 biopsy specimens were collected from 117 women with the human immunodeficiency virus. These specimens underwent central and local interpretation, which were compared and correlated with cytologic results.