Effect of Ejiao (Asini Corii Colla) and Turtle Carapace Glue on Gut Microbiota in Nude Mice with Uterine Fibroids Based on High-Throughput Sequencing of 16SrRNA Gene.

Objective: To observe the effects of Asini Corii Colla, turtle carapace glue, and other drugs on the intestinal flora of nude mice with uterine fibroids model, so as to provide evidence for the clinical application of drugs.

Methods: Set up five groups: blank control group, turtle carapace glue group, turtle carapace glue and ejiao 4 : 1 mixed group, turtle carapace glue and ejiao 1 : 1 mixed group, and turtle shell glue and (danshen) 1 : 1 mixed group. Then, the model nude mice were fed ejiao, turtle carapace glue, and other corresponding drugs.

Efficacy of Chinese herbal prescriptions containing Ejiao or Velvet antler for management of uterine fibroids: a systematic review and meta-analysis of randomized controlled trials.

Background: To evaluate the efficacy and safety of the controversial Chinese herbal prescriptions containing Ejiao or Velvet antler (VA) in the treatment of uterine fibroids.

Methods: We searched 4 famous Chinese databases, the Chinese Clinical Trial Registry, PubMed, Cochrane Central, Google Scholar, Embase, and J-STAGE up to July 2019. We included all eligible randomized controlled trials (RCTs) which compared Chinese herbal prescriptions containing Ejiao or VA (E/VA) with placebo, pharmaceutical intervention, surgery, or other traditional Chinese medicines (TCMs) for uterine fibroids and assessed the risk of bias according to the Cochrane Collaboration's tool.

Effects of shikonin from Zicao on high-fat diet-induced nonalcoholic fatty liver disease in rats.

In this study, we aim to investigate whether shikonin prevents against NAFLD. After feeding high-fat diet (HFD) for 10 weeks, Sprague-Dawley rats were received different doses of shikonin (5mg/kg/day, 10mg/kg/day and 20mg/kg/day) by gavage for the last 12 weeks of a total of 22 weeks of a HFD. Our results showed that total cholesterol (TC), triacylglycerol (TG), low-density lipoprotein cholesterol, aspartate aminotransferase and alanine aminotransferase were significantly increased, while high-density lipoprotein cholesterol was decrease, accompanied by hepatic injury and lipid accumulation in HFD-fed rats.

Protective Effect of Compound Formula Rehmannia against Neurotoxicity and Apoptosis Induced by -Syn in and Models of Parkinson's Disease.

The present study aimed to investigate the protective effect of compound formula Rehmannia (CFR) against the development of Parkinson's disease (PD). After the and models of PD were established with overexpression -syn induced, CFR was administrated into the PD model rats for 6 weeks or SK-N-SH cells with coincubation for 48 h. Apomorphine-induced rotation test, CCK8 assay, TUNEL assay, immunofluorescence staining, and western blot assay were performed to evaluate the behavioral changes, cell viability, cell apoptosis, -syn, GSK-3, P-GSK-3 (Ser9), P-GSK-3 (Tyr216), and -catenin expression in PD rats or SK-N-SH cells.

Acupuncture for hiccups: A systematic review protocol of high-quality randomized trials.

Background: A Hiccup is a common disease that often occurs along with other chronic or acute conditions. At present, there is a lack of feasible therapies for hiccups, and acupuncture is a treatment method with enormous clinical practice worldwide.

Methods: Based on a pre-defined search strategy, we searched seven databases and screened them by two independent investigators, without language and publication status restriction from inception to date.

Protective role of arnebin-1 in rats with nonalcoholic fatty liver disease.

Objective: To examine the effects of arnebin-1 on nonalcoholic fatty liver disease (NAFLD) induced by a high-fat diet (HFD).

Methods: Male Sprague-Dawley rats were fed an HFD for 10 weeks and then treated with arnebin-1 at a dose of 5, 10 or 20 mg/kg/day by gavage for a further 12 weeks of a 22-week HFD. Peripheral blood and liver tissues were collected for biochemical and histopathological examination.

Correlation between Traditional Chinese Medicine Constitution and Dyslipidemia: A Systematic Review and Meta-Analysis.

Objective: To study the correlation between Traditional Chinese Medicine (TCM) constitution and dyslipidemia.

Methods: CNKI, VIP, Wanfang database, CBMdisc, PubMed, and Embase were searched, and meta-analysis was performed by Review Manager 5.2 software.

Computer-aided tumor diagnosis using shear wave breast elastography.

The shear wave elastography (SWE) uses the acoustic radiation force to measure the stiffness of tissues and is less operator dependent in data acquisition compared to strain elastography. However, the reproducibility of the result is still interpreter dependent. The purpose of this study is to develop a computer-aided diagnosis (CAD) method to differentiate benign from malignant breast tumors using SWE images.

Intensity-Invariant Texture Analysis for Classification of BI-RADS Category 3 Breast Masses.

Radiologists likely incorrectly classify benign masses as Breast Imaging Reporting and Data System (BI-RADS) category 3. A computer-aided diagnosis (CAD) system was developed in this study as a second viewer to avoid misclassification of carcinomas. Sixty-nine biopsy-proven BI-RADS category 3 masses, including 21 malignant and 48 benign masses, were used to evaluate the CAD system.

Query-adaptive multiple instance learning for video instance retrieval.

Given a query image containing the object of interest (OOI), we propose a novel learning framework for retrieving relevant frames from the input video sequence. While techniques based on object matching have been applied to solve this task, their performance would be typically limited due to the lack of capabilities in handling variations in visual appearances of the OOI across video frames. Our proposed framework can be viewed as a weakly supervised approach, which only requires a small number of (randomly selected) relevant and irrelevant frames from the input video for performing satisfactory retrieval performance.

Robust Texture Analysis Using Multi-Resolution Gray-Scale Invariant Features for Breast Sonographic Tumor Diagnosis.

Computer-aided diagnosis (CAD) systems in gray-scale breast ultrasound images have the potential to reduce unnecessary biopsy of breast masses. The purpose of our study is to develop a robust CAD system based on the texture analysis. First, gray-scale invariant features are extracted from ultrasound images via multi-resolution ranklet transform.

Whole breast lesion detection using naive bayes classifier for portable ultrasound.

In recent years, portable PC-based ultrasound (US) imaging systems developed by some companies can provide an integrated computer environment for computer-aided diagnosis and detection applications. In this article, an automatic whole breast lesion detection system based on the naive Bayes classifier using the PC-based US system Terason t3000 (Terason Ultrasound, Burlington, MA, USA) with a hand-held probe is proposed. To easily retrieve the US images for any regions of the breast, a clock-based storing system is proposed to record the scanned US images.

Automatic selection of representative slice from cine-loops of real-time sonoelastography for classifying solid breast masses.

This study aimed to evaluate the performance of automatic selection of representative slice from cine-loops of real-time sonoelastography for classifying benign and malignant breast masses. This retrospective study included 141 ultrasound elastographic studies (93 benign and 48 malignant masses). A novel computer-assisted system was developed for the automatic segmentation of the targeted lesion from cine-loops of real-time sonoelastography.