Publications by authors named "Minchun Wang"
Context: Huangqi Guizhi Wuwu Decoction (HGWD) is effective in treating ischaemic stroke (IS). However, its mechanism of action is still unclear.
Objective: Network pharmacology integrated with experiments were used to clarify the underlying mechanisms of HGWD for treating IS.
Context: Paeoniflorin (PF) and calycosin-7-glucoside (CG, Pall. extract) have demonstrated protective effects in ischaemic stroke.
Objective: To investigate the synergistic effects of PF + CG on ischaemia/reperfusion injury and .
Canine Adenovirus 1 Isolation Bioinformatics Analysis of the Fiber.
Front Cell Infect Microbiol
July 2022
Canine adenovirus type 1 (CAdV-1) is a double-stranded DNA virus, which is the causative agent of fox encephalitis. The protein is one of the structural proteins in CAdV-1, which mediates virion binding to the coxsackievirus and adenovirus receptor on host cells. The suspected virus was cultured in the MDCK cells, and it was determined through the cytopathic effects, sequencing and electron microscopy.
View Article and Find Full Text PDFArticle Synopsis
- Canine adenoviruses include two types: CAdV-1 (virulent strain) and CAdV-2 (attenuated strain), with rising infection rates and challenging diagnosis due to similar symptoms.
- Differences in genome sequences, coding proteins, and pathogenicity exist between the two types, impacting transmission and response to infection.
- Current protections rely on a vaccine for CAdV-2 that might pose risks, highlighting the need for further research on their mechanisms and vaccine development.