Adaptive variable sampling model for performance analysis in high cache-performance computing environments.

High-performance computing provides computing power for a variety of scientific disciplines, supporting advancements by offering insights beyond metacognition. Maximizing computing performance without wasting resources is a major research issue. Predicting the performance of a computer's next state is effective for scheduling.

Complex disaster response framework to reduce urban disaster vulnerability.

Cities are vulnerable to a range of disasters that can occur simultaneously due to their complexity. Therefore, an effective disaster response plan is needed to reduce the disaster vulnerability of cities. In particular, evacuation route management is important for reducing the losses from a disaster.

Thiol-Rich fp-6 Controls the Tautomer Equilibrium of Oxidized Dopa in Interfacial Mussel Foot Proteins.

3,4-Dihydroxyphenylalanine (Dopa) is a versatile molecule that enables marine mussels to achieve successful underwater adhesion. However, due to its complicated redox chemistry and vulnerability to oxidation, controlling surface adhesion and cohesion has been a challenging issue to overcome. Foot protein type 6 (fp-6), a thiol-rich interfacial mussel adhesive protein, has been reported as a proteinaceous antioxidant for mussels that helps Dopa maintain surface adhesion ability.

Critical switching current density of magnetic tunnel junction with shape perpendicular magnetic anisotropy through the combination of spin-transfer and spin-orbit torques.

Recently, magnetic tunnel junctions (MTJs) with shape perpendicular magnetic anisotropy (S-PMA) have been studied extensively because they ensure high thermal stability at junctions smaller than 20 nm. Furthermore, spin-transfer torque (STT) and spin-orbit torque (SOT) hybrid switching, which guarantees fast magnetization switching and deterministic switching, has recently been achieved in experiments. In this study, the critical switching current density of the MTJ with S-PMA through the interplay of STT and SOT was investigated using theoretical and numerical methods.

Oriented in situ immobilization of a functional tyrosinase on microcrystalline cellulose effectively incorporates DOPA residues in bioengineered mussel adhesive protein.

Background: Catechol-containing polymers such as mussel adhesive proteins (MAPs) are attractive as biocompatible adhesive biomaterials, and the catecholic amino acid 3,4-dihydroxyphenyl-L-alanine (DOPA) is considered a key molecule in underwater mussel adhesion. Tyrosinases can specifically convert tyrosine to DOPA without any cofactors. However, their catalytic properties still need to be adjusted to minimize unwanted DOPA oxidation via their diphenolase activity and catechol instability at neutral and basic pH values in the reaction products.

Enhancement of perceived body ownership in virtual reality-based teleoperation may backfire in the execution of high-risk tasks.

Guided by previous research on the role of embodiment in virtual environments, this study aimed to investigate the potential effects of using human-like (compared to robotic) virtual hands on work performances in the context of virtual reality (VR)-based teleoperation of high-risk machinery. A 2 × 2 mixed factorial design experiment ( = 74), with the virtual hand representation as a within-subjects factor (robotic vs. human-like virtual hands) and the risk of danger as a between-subjects factor (low vs.

Harnessing the bioresponsive adhesion of immuno-bioglue for enhanced local immune checkpoint blockade therapy.

Despite the great promise of immune checkpoint blockade (ICB) therapy for cancer treatment, the currently available options for ICB treatment pose major clinical challenges, including the risk of severe systemic autoimmune responses. Here, we developed a novel localized delivery platform, immuno-bioglue (imuGlue), which is inspired by the intrinsic underwater adhesion properties of marine mussels and can allow the optimal retention of anti-PD-L1 drugs at tumor sites and the on-demand release of drugs in response to the tumor microenvironment. Using a triple-negative breast cancer and melanoma models, we found that imuGlue could significantly enhance anti-tumor efficacy by eliciting a robust T cell-mediated immune response while reducing systemic toxicity by preventing the rapid diffusion of anti-PD-L1 drugs into the systemic circulation and other tissues.

Enhanced production of Dopa-incorporated mussel adhesive protein using engineered translational machineries.

Mussel adhesive proteins (MAPs) have great potential as bioglues, particularly in wet conditions. Although in vivo residue-specific incorporation of 3,4-dihydroxyphenylalanine (Dopa) in tyrosine-auxotrophic Escherichia coli cells allows for production of Dopa-incorporated bioengineered MAPs (dMAPs), the low production yield hinders the practical application of dMAPs. This low production yield of dMAPs is due to low translational activity of a noncanonical amino acid, Dopa, in E.

The position of lysine controls the catechol-mediated surface adhesion and cohesion in underwater mussel adhesion.

Intensive studies have found that 3,4-dihydroxyphenylalanine (Dopa) is one of the key molecules for underwater mussel adhesion. Although basic mechanisms of mussel adhesion have been elucidated, little is known about how mussels control the balance between surface adhesion and cohesion, which is critical for successful adhesion without peeling and/or tearing. In this work, we focused on lysine (Lys) molecules which are frequently flanked to Dopa residues in interfacial adhesive proteins, specifically their synergy and anti-synergy on surface adhesion and cohesion.

Uncanny Valley Effects on Friendship Decisions in Virtual Social Networking Service.

Drawing on the uncanny valley effects (UVE) hypothesis and related works on avatar-based interactions, this study investigates the role of UVE (i.e., a feeling of eeriness), induced by avatar realism and animacy, on the perceived trustworthiness (PT) of an avatar user, and subsequent decisions to befriend that avatar user in a virtual social networking service (SNS).

CASS: A distributed network clustering algorithm based on structure similarity for large-scale network.

As the size of networks increases, it is becoming important to analyze large-scale network data. A network clustering algorithm is useful for analysis of network data. Conventional network clustering algorithms in a single machine environment rather than a parallel machine environment are actively being researched.

Phase difference dependence of output power in synchronized stacked spin Hall nano-oscillators.

Synchronization between stacked spin Hall nano-oscillators (SHNO), attributed to the spin Hall effect and anisotropic magnetoresistance effect, was studied by numerical calculations. In order to obtain the synchronized state of the SHNOs, we considered the magneto-dipolar field, which was calculated in the rectangular prism. We revealed that the output power depended on the distance between the SHNOs, as the phase difference between the SHNOs depended on the coupling strength.

Effects of Si/SiO interface stress on the performance of ultra-thin-body field effect transistors: a first-principles study.

First-principles density functional theory (DFT) based device simulations are performed for Si ultra-thin-body (UTB) field effect transistors with the explicit SiO atoms in the gate dielectric. In order to evaluate the Si/SiO interface stress effects on the UTB device performance, the interface stress tensor is extracted from the Si/SiO atomic structure by DFT calculations. The influence of the interface stress on the transport properties is examined through full quantum mechanical non-equilibrium Green's function calculations.

To Be Connected or Not To Be Connected? Mobile Messenger Overload, Fatigue, and Mobile Shunning.

With the increased adoption of mobile devices, mobile communication is all around us and we are connected anywhere, anytime. Mobile communication in general and mobile messenger service in particular make interpersonal communication in Korea so frequent and convenient. However, being connected too much anywhere and anytime via mobile messenger service appears to lead an increasing number of people to feel fatigue and to decrease mobile communication under some conditions.

Nonorthogonal [Formula: see text] tight-binding parameterization of single-layer phosphorene under biaxial strain and application to FETs.

This paper presents a new set of [Formula: see text] tight-binding (TB) parameters for single-layer phosphorene within the Naval Research Laboratory (NRL) scheme. For this, we develop the numerical algorithm to find the NRL TB parameters fitted to ab initio results. It is shown that the proposed NRL TB parameters successfully reproduce the band structure of a single-layer phosphorene, and even under biaxial or uniaxial strain, they appropriately describe the effects, such as modification of anisotropic effective masses and band gap.

The Augmented Cognitive Mediation Model: Examining Antecedents of Factual and Structural Breast Cancer Knowledge Among Singaporean Women.

As knowledge acquisition is an important component of health communication research, this study examines factors associated with Singaporean women's breast cancer knowledge using an augmented cognitive mediation model. We conducted a nationally representative study that surveyed 802 women between the ages of 30 and 70 using random-digit dialing. The results supported the augmented cognitive mediation model, which proposes the inclusion of risk perception as a motivator of health information seeking and structural knowledge as an additional knowledge dimension.

Spin nano-oscillator-based wireless communication.

Spin-torque nano-oscillators (STNOs) have outstanding advantages of a high degree of compactness, high-frequency tunability, and good compatibility with the standard complementary metal-oxide-semiconductor process, which offer prospects for future wireless communication. There have as yet been no reports on wireless communication using STNOs, since the STNOs also have notable disadvantages such as lower output power and poorer spectral purity in comparison with those of LC voltage-controlled oscillators. Here we show that wireless communication is achieved by a proper choice of modulation scheme despite these drawbacks of STNOs.

Effect of silicide/silicon hetero-junction structure on thermal conductivity and Seebeck coefficient.

We fabricated a thermoelectric device with a silicide/silicon laminated hetero-structure by using RF sputtering and rapid thermal annealing. The device was observed to have Ohmic characteristics by I-V measurement. The temperature differences and Seebeck coefficients of the proposed silicide/silicon laminated and bulk structure were measured.

The influence of ionized impurity scattering on the thermopower of Si nanowires.

The thermopower of Si nanowires was investigated on the basis of electronic transport theory, taking into account ionized impurity scattering as well as electron-phonon scattering. It was found that the enhancement of the Seebeck coefficient in nanowires arising from quantum confinement is unimportant due to the ionized impurity scattering associated with donor deactivation. Furthermore, because the electrical conductivity is degraded significantly as the nanowire size becomes smaller, despite the accompanying slightly enhanced Seebeck coefficient, the reduction of the nanowire size is not beneficial, at least for the thermopower of devices.

Quantum mechanical simulation of hole transport in p-type Si Schottky barrier MOSFETs.

A full quantum-mechanical simulation of p-type nanowire Schottky barrier metal oxide silicon field effect transistors (SB-MOSFETs) is performed by solving the three-dimensional Schrödinger and Poisson's equations self-consistently. The non-equilibrium Green's function (NEGF) approach is adopted to treat hole transport, especially quantum tunneling through SB. In this work, p-type nanowire SB-MOSFETs are simulated based on the 3-band k.

Hole-effective masses in the transport calculation of Si nanowire pMOSFETs.

The full-quantum, self-consistent simulation of p-type silicon nanowire field effect transistors based on the k * p method is performed and their device characteristics are examined in the light of the hole-effective masses. An attempt is made in this study to assess the role of the hole-effective masses by devising simple, single-band parabolic effective mass (PEM) Hamiltonians and comparing the transport characteristics with the ones from the k * p method. It is found that the PEM Hamiltonian with isotropic effective masses fails to correctly produce both the scaling behavior of the subthreshold currents and the behavior of the on-currents with respect to the silicon orientation.

Maximization of acoustic energy difference between two spaces.

There has recently been an increasing interest in the generation of a sound field that is audible in one spatial region and inaudible in an adjacent region. The method proposed here ensures the control of the amplitude and phase of multiple acoustic sources in order to maximize the acoustic energy difference between two adjacent regions while also ensuring that evenly distributed source strengths are used. The performance of the method proposed is evaluated by computer simulations and experiments with real loudspeaker arrays in the shape of a circle and a sphere.

Aqueous humor and plasma levels of vascular endothelial growth factor and interleukin-8 in patients with central serous chorioretinopathy.

Purpose: The purpose of this study was to determine aqueous vascular endothelial growth factor (VEGF) and interleukin-8 (IL-8) levels in patients with central serous chori-oretinopathy (CSC) before a single intravitreal bevacizumab injection.

Methods: Twelve eyes with symptomatic CSC were included. Samples from patients with cataracts served as controls.

Stenotrophomonas daejeonensis sp. nov., isolated from sewage.

A Gram-stain-negative, motile, aerobic bacterial strain, designated MJ03(T), was isolated from sewage and was characterized taxonomically by using a polyphasic approach. Comparative 16S rRNA gene sequence analysis showed that strain MJ03(T) belongs to the family Xanthomonadaceae, class Gammaproteobacteria, and was related most closely to Stenotrophomonas acidaminiphila AMX 19(T) (97.9  % sequence similarity), Stenotrophomonas humi R-32729(T) (97.

Pegylated-interferon-associated retinopathy in chronic hepatitis patients.

Purpose: To investigate the clinical features of pegylated-interferon (PEG-IFN)-associated retinopathy in chronic hepatitis patients.

Methods: We examined a consecutive case series of 46 patients who were treated with PEG-IFN for chronic hepatitis C or B between October 2007 and September 2008. All patients underwent regular ophthalmologic examinations every 3 weeks during the 6 months after treatment.