Method of prevention of post-operative peritoneal adhesions.

Objective: The purpose of the research was to assess the performance of the method of prevention of post-operative peritoneal adhesions (PAs) (author's method) in patients of different age groups.

Methods: Two hundred eighty-five patients were in total enrolled in the study. The patients of two age groups were divided into two groups: Group 1 (treatment group), where the author's method was used on 143 patients, and Group 2 (control group) 142 patients, where was used the standard approach of prevention of intra-abdominal adhesions.

[Influence of connective tissue differentiation on scar tissue formation in children].

Objective: To study the immunohistochemical features of various scar tissues in children without connective tissue pathology and with undifferentiated connective tissue dysplasia syndrome.

Material And Methods: Tissue biopsy was performed in 217 children who underwent surgical treatment for various lesions, such as injuries, burns, as well as other procedures. There were 127 boys (58.

Deep learning for early detection of pathological changes in X-ray bone microstructures: case of osteoarthritis.

Texture features are designed to quantitatively evaluate patterns of spatial distribution of image pixels for purposes of image analysis and interpretation. Unexplained variations in the texture patterns often lead to misinterpretation and undesirable consequences in medical image analysis. In this paper we explore the ability of machine learning (ML) methods to design a radiology test of Osteoarthritis (OA) at early stage when the number of patients' cases is small.

[Multicenter study of the effectiveness of antiscar therapy in patients at different age periods].

Objective: Was to evaluate the effectiveness of anti-scar treatment with Contractubex gel in children and adults.

Material And Methods: A group of researchers based on clinical hospitals and university medical clinics carry out the multicenter study to evaluate the effectiveness of anti-scar treatment with Contractubex gel containing cepalin, allantoin and heparin, with its early appointment in groups of children from 12 to 18 years old and adults from 21 to 35 years old. The study included data from 216 patients.

[3d-technologies in hepatobiliary surgery].

The authors describe modern 3D technologies in hepatobiliary surgery. These approaches reduce the risk of intra- and postoperative complications. Virtual 3D reconstruction with clear visualization of parasitic cyst, adjacent vessels and bile ducts is valuable to create 3D-model of liver.

[Multi- and single-port laparoscopic surgery in the treatment of hydatid liver disease].

Objective: To compare the effectiveness of multi-port and single-port laparoscopic surgery in the treatment of hydatid cyst of the liver.

Material And Methods: There were 25 children with solitary hydatid cyst of the liver (CL-CE2) who underwent surgery in 2013-2017. Mean age was 10.

[Results of a clinical study of a new anxiolytic, a blocker of central cholecystokinin receptors].

Aim: To evaluate anxiolytic action of GB-115, a low-affinity blocker of central cholecystokinin receptors, used in tablets in a dose of 1 mg for the treatment of patients with anxiety disorders in order to determine effective dose, safety, tolerability and efficacy in clinical settings.

Material And Methods: The study included 31 patients (22 women, 9 men) diagnosed with generalized anxiety disorder (GAD, F41.1 according to ICD-10), aged from 22 to 53 years.

[Comparison of different methos of compression of scars with prolonged release plate].

Unlabelled: The purpose of the study was to compare the effectiveness of various compression techniques with a prolonged-action patch on postoperative scars.

Material And Methods: The study included 21 patients aged 3.6±1.

Surgical treatment of idiopathic megarectum in constipated children.

Background: Chronic constipation in children is associated with primary megarectum. This study investigated outcomes of surgical treatment of idiopathic megarectum in children.

Methods: This retrospective comparative study included 52 children with idiopathic megarectum (mean age, 9.

[A new approach in the compression therapy of postoperative scars].

Unlabelled: The aim of the study was to evaluate the effectiveness of compression therapy with a prolonged plaster of Contractubex in the formation of skin scarring in children after surgery.

Material And Methods: In a prospective open-label randomized trial, 109 patients aged 5.3±2.

Laparoscopic Treatment in Children with Hydatid Cyst of the Liver.

Background: There is no consensus on the surgical treatment of children with hydatid cyst of the liver (HCL). We evaluated the outcomes of laparoscopic and open surgery for childhood HCL.

Methods: We performed 81 open surgery and laparoscopic procedures in 37 (45.

[The complications of intestinal stoma in children].

Aim: To investigate the complications of intestinal stoma in children and to develop measures for decrease of their incidence.

Material And Methods: The study included 152 children with congenital and acquired gastrointestinal pathology requiring surgical treatment with the imposition of intestinal stoma. Atresia of intestinal tube was observed in 28 (18.

[Personalized method of oral hygiene quality control].

In the study involving 110 patients (58 males aged 25-59 and 52 females aged 25-53) a method of oral hygiene quality control by means of new dental index was introduced which allows adequate oral hygiene assessment, personalized recommendations aimed at reducing the risk of common dental diseases development and monitoring of the implementation of these recommendations by patients.

Outcome of Laparoscopic Treatment of Anorectal Malformations in Children.

Background: Operative correction of anorectal malformations (ARMs) remains a challenge in pediatric surgery. The study aimed to evaluate the outcomes of laparoscopic treatment of ARM in children.

Methods: From 2007 to 2014, we performed 104 laparoscopic-assisted anorectal pull-through procedures in children with a mean age of 11.

Molecular ion sources for low energy semiconductor ion implantation (invited).

Smaller semiconductors require shallow, low energy ion implantation, resulting space charge effects, which reduced beam currents and production rates. To increase production rates, molecular ions are used. Boron and phosphorous (or arsenic) implantation is needed for P-type and N-type semiconductors, respectively.

[Recombinant granulocyte-colony stimulating factor (filgrastim): optimization of conditions of isolation and purification from inclusion body].

We developed a unified process platform for two recombinant human GCSF medicines--one with the non-prolonged and the other with prolonged action. This unified technology led to a simpler and cheaper production while introduction of the additional pegylation stage to the technological line eased obtaining of the medicines with different action and allowed to standardize technological process documenting according to GMP requirements.

[Meta-analysis: the possibility of atrophy of testicle in acute testicular appendage problems in children].

A meta-analysis of extensive statistical data of "acute scrotal" syndrome in children was made. The two databases were considered. The first consisted of 1342 observations and described the nosologic structure of "acute scrotal" syndrome in children.

[Up-to-date approaches in treatment of hydatid disease of the liver in childhood].

Sixty children (age 3-15 years) with hydatid disease of the liver were treated. The patients were divided into 2 equal groups (control and main groups).The hydatid disease of the liver was revealed in 22 (33.

[The surgical treatment of varicocele in children and adolescents in the outpatient setting].

The first group included 45 patients with varicocele stage I--II; the second group included 20 patients with varicocele stage III. The ambulatory treatment complex permitted the inmprovement of of ultrasound indexes in scrotal veins in 29 (64%) patients of the 1st group, whereas nobody of the 2nd group showed any isignificant improvement. The proper use of the worked out complex allows the pathogenetic and correct treatment of varicocele in adolescents.

[The surface anesthesia in outpatient pediatric department].

The combination of even parts lidocaine and prilocaine in crème substance was used for surface anesthesia in 73 children, aged 1,5-16 years. Such surgical interventions as molluscum contagiosum eradication, laser wart resection and prepuce synechia dissection were performed. The described anesthetic was highly effective in all areas, but the nasolabial triangle.

The influence of enzymes on adhesive processes in the abdominal cavity.

Introduction: Intraperitoneal adhesions remain a common problem after abdominal surgery. However, the advent of targeted, specific agents as a directed therapy against inflammatory and neoangiogenesis raises the prospect of a new approach for anti-adhesion strategies.

Methods: 70 adult rats were divided into two groups: an enzyme group (35 rats) and a control group (35 rats).

[Complex treatment of acute hematogenous osteomyelitis in children].

The acute hematogenous osteomyelitis continues to remain at present one of the actual problems to pediatric surgery, being characterized by severe course, difficulty of the early diagnostics and frequency of unfavourable outcomes, becoming chronic and complications. We investigated the levels of CRP, IL-1beta, TNF-alpha in 74 children with acute hematogenous osteomyelitis. In the first (control) group children had standart therapy, in the second (main) group children had standart therapy with Licopid.